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Biochemistry I

Code: MIMD010103     Acronym: BIOQ I

Keywords
Classification Keyword
OFICIAL Physical Sciences

Instance: 2025/2026 - 1S Ícone do Moodle

Active? Yes
Responsible unit: Mestrado Integrado
Course/CS Responsible: Integrated Master in Dental Medicine

Cycles of Study/Courses

Acronym No. of Students Study Plan Curricular Years Credits UCN Credits ECTS Contact hours Total Time
MIMD 1 Official Plan from the academic year 2020/2021 1 - 5 81 135
NÃO INSCREVER - Plano exclusivo para uso administrativo 1 - 5 81 135

Teaching Staff - Responsibilities

Teacher Responsibility
Maria Adelina Coelho Ribeiro Costa

Teaching - Hours

Theoretical classes: 1,00
Theoretical and practical : 1,50
Laboratory Practice: 2,00
Type Teacher Classes Hour
Theoretical classes Totals 1 1,00
André Moreira Neto da Silva 0,428
Maria Adelina Coelho Ribeiro Costa 1,071
Theoretical and practical Totals 1 1,50
André Moreira Neto da Silva 0,428
Maria Adelina Coelho Ribeiro Costa 1,071
Laboratory Practice Totals 4 8,00
Luís Manuel de Mira Vieira 2,50
Maria Adelina Coelho Ribeiro Costa 2,50
Maria Antónia Santos Mendes Salgado 5,00

Teaching language

Portuguese

Objectives

1. To rationalize living systems in terms of basic Chemistry principles. To present Biological Chemistry as a mere subset of Chemistry.
2. To correlate knowledge from Organic and Inorganic Chemistry with Biological Chemistry.
3. To acquire specific knowledge about biological molecules and the cellular chemical organization.
4. Aspects of the specific Biological Chemistry of saliva.
5. To acquire some practical skills on chemical, biochemical and spectroscopic laboratorial methods.

Learning outcomes and competences


1. Knowledge of the biologically important carbon compounds reactions and their mechanisms. 


2. Structural knowledge of the most important types of biological molecules.


3. Understanding of the importance of molecular recognition, intermolecular interaction and the hydrophobic effect in biological chemistry.


4. Ability to explain the function and action mechanism of biological compounds based on its molecular structure and reactivity, namely enzymes' catalysis, kinetics and regulation.


5. Understanding of the main metabolism global organization, namely the integration of anabolism and catabolism made by NAD (and FAD) and ATP (and other NTPs).


Working method

Presencial

Program

THEORETICAL AND THEORETICAL-PRACTICAL CLASSES

1. Elements of General Chemistry: acid/base equilibrium, pH buffers; solubility equilibrium.
2. Organic Chemistry elements.
3. Structure and function of biological molecules: carbohidrates, lipids, proteins, nucleic acids; kinetic and thermodynamic stability; intermolecular bonding and molecular recognition.
4. Enzymes: catalysis, selectivity, kinetics (Michaelis-Menten) and regulation.
5. Aspects of oral biological chemistry: organic/inorganic composition of saliva; functions of the different components.
6. UV/VIS spectrophotometry; Interpretation and treatment of experimental data.

LABORATORIAL CLASSES

Preparation and spectrophotometric dosing of solutions.
Potentiometric carbonate titration.
Sugar identification reactions.
Biological pigments: qualitative analysis by UV-Vis.
Kinetics of enzymatic hydrolysis of sucrose.
Denaturation and spectrophotometric analysis of DNA.

 

Mandatory literature

T.W. Graham Solomons and Craig B. Fryhle; Organic Chemistry, John Wiley & Son, Inc, 10th Edition., 2011
Nelson , David L.; Lehninger Principles of Biochemistry. ISBN: 978-0-7167-7108-1
K. Peter, C, Vollhardt, Neil E. Schore; Organic Chemistry Structure and Function, W. H. Freeman and Company, New York, 4th Edition., 2003

Complementary Bibliography

José Antonio Ramos Atance,; Bioquímica bucodental. ISBN: 84-7738-350-2

Teaching methods and learning activities

Theoretical classes consist of oral and PowerPoint presentation of the different programmatic topics, with continuous interaction with the students.

Theoretical-practical classes for the elaboration of exercises related to the syllabus of the course.

Practical classes involving laboratory experiments.

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Designation Weight (%)
Exame 100,00
Total: 100,00

Amount of time allocated to each course unit

Designation Time (hours)
Estudo autónomo 58,00
Frequência das aulas 57,00
Trabalho laboratorial 20,00
Total: 135,00

Eligibility for exams

According to the General Regulation of the University of Porto Learners Assessment is considered a student fulfills the attendance to a course if, having been regularly enrolled, does not exceed the number limit faults corresponding to 25% of the foreseen classes, as regulated in the existing organizational unit.

Calculation formula of final grade

Denomination of assessments (all graded at 20 points):
A1 (1st frequency taken in Intermediate Assessment 1),
A2 (2nd frequency taken in Normal season),
EN (overall exam taken in Ordinary period)
ER (overall exam taken in Appeal period).

Options for approval, Final grade, F ≥ 9.50 values:

(1) F = 0.5 x A1 + 0.5 x A2 
(2) F = EN
(2) F = ER

A2 and EN assessments are simultaneous and thus mutually exclusive. It is possible to switch from option (1) to options (2) or (3) but this means permanently discarding the mark obtained in A1.

Examinations or Special Assignments

 

Special assessment (TE, DA, ...)

The exam will consist of the same test that is taken by students taking the final exam or the appeal exam.

Classification improvement

In accordance with the rules of the University of Porto Regulations.
The exam will consist of the same test that is taken by students taking the final exam or the appeal exam.
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