Pharmacology

Code:

MD2402

Acronym:

F

Keywords
Classification	Keyword
OFICIAL	Clinical pharmacology

Instance: 2017/2018 - 2S

Active?	Yes
Responsible unit:	Mestrado Integrado
Course/CS Responsible:	Integrated Master in Dental Medicine

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MIMD	69	PLANO OFICIAL 2007/2008 BOLONHA	2	-	3,5	54	94,5

Teaching language

Portuguese

Objectives

Teaching on "Pharmacology" (2nd year, 2nd semester) aims at providing substantial pharmacological knowledge, in order to allow the understanding of subsequent course units related to therapeutics. It has two main objectives:
- knowledge acquisition in General pharmacology, namely, the basic pharmacological concepts, to the development of skills in the understanding and application of the principles of pharmacology, common to the use of any drug.
- knowledge acquisition in the pharmacology of drugs with actions in several body systems (pharmacology of the vegetative nervous system and pharmacology of the endocrine system). Addicionally, the understanding of toxics and intoxications.

Learning outcomes and competences

The course is set on a structural approach with growing complexicity of its syllabus. Initially, basic concepts are introduced in the "General principles of pharmacology". Knowledge of the concepts that are common to the use of any drug, as the kinetic behavior in the body, the general mechanisms of action and the evaluation of the therapeutic effects are are essential for the rational use of drugs. Next, the pharmacology of the vegetative nervous system and the pharmacology of the endocrine system are addressed, allowing the illustration, application and integration of the basic concepts taught previously in the understanding of the pharmacological profile of drugs or drug groups that have multisystemic actions. The syllabus also includes the toxics and intoxications.
This approach gradually instills the importance of an integrated vision of the pharmacological profile of a drug, in the optimization of the risk/benefit ratio.

Working method

Presencial

Program

I. General principles of pharmacology

1. Introduction to pharmacology
2. General concepts
3. Mechanisms of drug action
General principles
Molecular aspects
Cellular aspects
4. Pharmacokinetics
Passage of drugs across membranes
Absorption and distribution of drugs
Drug elimination
5. Individual variation to drug response
6. Harmful effects of drugs
7. Drug interactions
8. Biopharmaceuticals. Gene therapy
9. Method and measurement in pharmacology
10. Drug discovery and development

II. Pharmacology of the Peripheral Nervous System

1. Drugs affecting cholinergic transmission
2. Drugs affecting adrenergic transmission

III. Endocrine system

1. Hypothalam
2. Pituitary
3. Thyroid
4. Adrenal cortex
5. Endocrine pancreas and the control of blood glucose
6. Obesity
7. Reproductive system
8. Bone metabolism. 

IV: Toxics and intoxications



Bibliography

“Rang and Dale’s Pharmacology”, 7th edition
Rang HP, Dale MM, Ritter JM, Flower RJ, Henderson G. Churchill Livingstone, 2012.

“Terapêutica medicamentosa e suas bases farmacológicas”, 6ª edição. Serafim Guimarães, Daniel Moura, Patrício Soares da Silva. Porto Editora, 2013.

“Pharmacology and Therapeutics for Dentistry”, 6ª edição. Yagiela JA, Dowd FJ, Johnson BS, Mariotti AJ, Neidle EA, Mosby, 2011

Prontuário Terapêutico. Infarmed. Ministério da Saúde.

Mandatory literature

Yagiela John A.; Pharmacology and therapeutics for dentistry. ISBN: 978-0-323-05593-2
Rang H.P.; Rang and Dale.s pharmacology. ISBN: 978-0-7020-3471-8

Teaching methods and learning activities

“Pharmacology” is organized in theoretical (T; 1h/semana/estudante), theoretical-practical (TP) and practical (P) lectures.
T lectures are participated classes that aim to introduce new concepts of the selected topic.
TP and P classes, with a participated tutorial approach, based in a problem-based learning approach, which aims to expand and strengthen the concepts developed with T lectures. In P lectures, the students are distributed in 4 classes, and organized in working groups.

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Designation	Weight (%)
Exame	70,00
Participação presencial	10,00
Teste	10,00
Trabalho escrito	10,00
Total:	100,00

Eligibility for exams

According to the established by the Pedagogical Council of FMDUP.

To meet the following requirements of the continuous evaluation:

- Presentation, resolution and discussion of case-problems/clinical cases during P lectures (10% of the final classification)
- Presentation of an issue related with the syllabus, in a TP lecture (10% of the final classification) 
- Test focusing a integrative clinical case, at the end of the semester (10% of the final classification)

Calculation formula of final grade

The evaluation focuses on the integration of knowledge and decision making. The final classification  includes the components of continuous evaluation and the final examination.

- Continuous evaluation – 30% (0 to 6, out of 20) (A)
1. Presentation, resolution and discussion of case-problems/clinical cases during P lectures: 10%;
2. Presentation of an issue related with the syllabus, in a TP lecture: 10%;
3. Test focusing a integrative clinical case, at the end of the semester: 10%).

- Final examination: 70% (0 to 14, out of 20) (B)

Final classification: A + B

Minimal classification for approval: 10

Maximal classification: 20

Classification improvement

According to the established by the Pedagogical Council of FMDUP.