Biochemistry I

Code:

MD1103

Acronym:

B I

Keywords
Classification	Keyword
OFICIAL	Physical Sciences

Instance: 2012/2013 - 1S

Active?	Yes
Web Page:	http://moodle.up.pt/course/view.php?id=474
Responsible unit:	Mestrado Integrado
Course/CS Responsible:	Integrated Master in Dental Medicine

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MIMD	88	PLANO OFICIAL 2007/2008 BOLONHA	1	-	6	81	162

Teaching language

Portuguese

Objectives

- Aquisition of knowledge about the fundamentals of Biochemistry and its relationship with daily life phenomenons.
- Skills of analysis, integration and discussion of aquired knowledge.
- Development of identification and interpretation skills of new situations related with aquired knowledge.
- Aquisition of laboratorial work skills.
- Understanding the relevance of Biochemistry experimental methods as a lerning basis and its aplication in Medical Sciences.

Program

THEORETICAL AND THEORETCIAL-PRACTICAL CLASSES
- Introduction to biological processes:
Organic chemistry fundaments. Acids and bases.
- Structure and function of organic biomolecules:
Carbohydrates. Lipids. Proteins. Nucleic acids.
- Enzymes and enzimatic catalysis.
- Oral biochemistry:
Saliva composition. Buffer sistems of saliva. Teeth composition. Fluoride biochemistry.



PRACTICAL CLASSES
- Laboratory safety rules.
- Significative algarisms.
- Concentration of solutions.
- Preparation of solutions with exact concentration.
- pH determination of a solution.
- Carbohydrates identification.
- Extraction and analysis by thin layer chromatography of egg yolk lipids.
- Extraction and quantitation of egg yolk cholesterol.
- Protein identification.
- Protein quantification of a sample.
- Preparation and running of a SDS-PAGE gel.
- Protein isoelectric point determination.
- Study of salliva's composition.

Mandatory literature

Quintas A, Freire AP, Halpern MJ; Bioquímica – Organização Molecular da Vida, Lidel, 2008
Nelson David L.; Lehninger principles of biochemistry. ISBN: 0-7167-4339-6
Blackman A, Bottle S, Schmid S, Mocerino M, Wille U; Chemistry, John Wiley & Sons Ltd, 2008
Ferguson David B.; Oral Bioscience. ISBN: 0-7552-0229-5

Teaching methods and learning activities

Weekly classes / student

1 theoretical class of 60 minutes
1 theoretical-practical class of 90 minutes
1 practical class of 120 minutes

keywords

General programmes > Basic programmes > Basic programmes
General programmes > Basic programmes
Social Sciences, Commerce and Law > Basic programmes
General programmes > Basic programmes
Natural sciences
Natural sciences > Biological sciences
Health sciences

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Description	Type	Time (hours)	Weight (%)	End date
Attendance (estimated)	Participação presencial	85,50
Final report about one experience made during the semester.	Trabalho escrito
Mini-reports related with experiences made. They are made in the classes, after the practical work.	Trabalho escrito
Two worksheets about themes related with the contents of the discipline. They will be made with bibliographic consult and/or with Internet.	Trabalho escrito
Calculation test about: significatif algarisms, concentration of solutions, pH of buffer solutions.	Exame
Final exam.	Exame
	Total:	-	0,00

Amount of time allocated to each course unit

Description	Type	Time (hours)	End date
The presence in the classes will be evaluated.	Frequência das aulas
	Total:	0,00

Eligibility for exams

Presence in 3/4 of the classes.
Minimum classification in the continuous evaluation (excluding presence in the classes) of 4,05 values.
Elaboration of 2 intermediate exams (minimum average = 4,05 values) OR final exam (minimum classification= 4,05 values; maximum = 9 values)

Calculation formula of final grade

Classification in intermediates or final written exam (maximum = 9 values) + classification in mini-reports made in practical classes (maximum = 2 values) + classification in the final report (maximum = 1 values) + classification in the worksheets (maximum = 2 values) + classification in the calculation test (maximum = 4 values) + presence in the classes (maximum = 2 values)

Minimal classification for approval = 10 values

Observations

Schedule of students support:
- Monday from 13h30m to 16h00m
- Thursday from 12h30m to 16h00m