Pharmacology and Therapeutics I

Code:

MD3504

Acronym:

FT I

Keywords
Classification	Keyword
OFICIAL	Clinical pharmacology

Instance: 2008/2009 - 1S

Active?	Yes
Course/CS Responsible:	Integrated Master in Dental Medicine

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MIMD	75	Plano de Transição 2º Ano Bolonha 2007	3	-	4	54	108

Teaching language

Portuguese

Objectives

1. Knowledge of the pharmacology of the pain and inflammation, antimicrobial drugs and agents affecting hemostasis, because of their relevance in dentistry.
2. Knowledge of the pharmacology of the principal systems (cardiovascular, respiratory, gastrointestinal and endocrine). For these groups of drugs, implications for dentistry are also addressed, namely adverse drug reactions in the oral cavity, precautions and interactions with the drugs used/prescribed by the dental professional.
3. Approach to some special topics in dentistry, namely the use of fluoride as an anticarie agent, conscious sedation, antibiotic prophylaxis and a systematization of the adverse drug reactions in the oral cavity and the relevant drug interactions.

Program

I. PHARMACOLOGY OF THE PAIN
Nonsteroidal Anti-inflammatory drugs
Paracetamol
Combination analgesics
Opioid analgesics and antagonists
Local anesthetics
Fármacos used in general anesthesia

II. ANTIMICROBIAL CHEMOTHERAPY
Antibacterial drugs
Antifungal drugs
Antiviral agents

III. ANTISEPTICS AND DISINFECTANTS

IV. PHARMACOLOGY OF THE CARDIOVASCULAR SYSTEM
Antihypertensive drugs.
Antiarrhythmic drugs. Antianginal drugs. Drugs used in heart failure
Lipid-lowering drugs
Antianemic and hematopoietic stimulating drugs
Implications for dentistry

V. AGENTS AFFECTING HEMOSTASIS
Procoagulant agents
Anticoagulants
Fibrinolytics and antifibrinolytics
Platelet inhibitors
Implications for dentistry

VI. PHARMACOLOGY OF THE RESPIRATORY SYSTEM
Drugs used to treat asthma. Antitussives. Expectorants and mucolytics. Nasal decongestants
Implications for dentistry

VII. PHARMACOLOGY OF THE GASTROINTESTINAL TRACT
Drugs used in peptic ulcer therapy. Antiemetics. Emetics. Laxatives. Antidiarrheal agents. Antispasmodicsos. Intestinal anti-inflammatory agents. Drugs affecting the biliar system. Enzymatic inhibitors
Implications for dentistry

VIII. PHARMACOLOGY OF THE ENDOCRINE SYSTEM
Hypothalam
Pituitary
Thyroid
Adrenal cortex
Endocrine pancreas and the control of blood glucose
Obesity
Reproductive system
Bone metabolism
Implications for dentistry

IX. ANTINEOPLASTIC DRUGS AND IMMUNOPHARMACOLOGY
Antineoplastic drugs
Imunosuppressive/antiinflammatory drugs. Immunostimulatory drugs
Implications for dentistry

X. SPECIAL TOPICS
Fluoride
Antibiotic prophylaxis in dentistry
Conscious sedation in dentistry
Adverse drug reactions on the oral cavity
Drug interactions in dentistry
Drug abuse



BIBLIOGRAPHY

Main bibliography:
• “Pharmacology and Therapeutics for Dentistry”, 6th edition. J.A. Yagiela, E.A. Neidle, F.J. Dowd. Mosby, 2005
• “Katzung & Trevors’s Pharmacology”
Trevor AJ, Katzung BG, Masters S. 8ª Edição. Lange 2008

Complementar bibliography:
• “Farmacologia e Terapêutica em Medicina Dentária”
Maria Helena Fernandes. Medisa, 2006
• "Terapêutica medicamentosa e suas bases farmacológicas", 4ª edição. Coordenação de S. Guimarães e P. Soares da Silva. Porto Editora, 2005.
• Recent articles and reviews

Teaching methods and learning activities

Teaching time / week / student:
1 theoretical class (60 minutes)
1 theoretical-practical / practical class (120 minutes)

Evaluation Type

Distributed evaluation with final exam

Calculation formula of final grade

1. Normal assessment

• Continuous evaluation (A) = 10 (out for 10)

a) Monograph + Poster = 2 (out of 10)
b) Evaluation during the practical lessons = 3 (out of 10)
c) 3 Minitests = 5 (out of 10)
(adverse drug reactions and drug interactions of the several drug groups)

• Final evaluation (B) = 10 (out of 20)

Final examination test
(mechanisms of action, pharmacological actions, clinical use of the several drug groups)

Final classification = A + B / 2

Minimum classification for approval = 10 (out of 20)


2. Second opportunity assessment

Minimum classification for approval = 10 (out of 20)