Imunology

Code:

302

Acronym:

302

Instance: 2004/2005 - A

Active?	Yes
Web Page:	http://webct.up.pt/webct/public/home.pl
Course/CS Responsible:

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MD	57	Plano oficial a partir de 2000	3	4	7	-

Objectives

Knowledge on the functional characteristics of the Immunological System, especially on its effector components and its role on the biological response to injury. Knowledge on the main immunological mechanisms involved in the regulation of the inflammatory response, on hypersensitivity mechanisms and on immunological diagnostic and therapeutical approach of human pathology. Immunological mechanisms in commun oral disease, as well as the oral envolvement of the main immunopathological syndromes of immunopathology affecting the oral cavity.

Program

Theoretical subjects:
Immunological reaction. The Immunological System. B-lymphocytes. T-lymphocytes. Antigens. Major Histocompatibility Complex. Immunological Tolerance. Effector mechanisms and theamplification of immunological reaction. Regulation of immunological response. Immunity and infection. Primary Immunodeficiencies. Secondary immunodeficiencies. Immunological hypersensitivity reactions. Immunopathology of hypersensitivity diseases - type I, II, III and IV. Autoimmune diseases. Organ specific and non organ specific Autoimmune diseases. Immunity and cancer. Transplantation. Immunomodulation.
Theoretical-Practical Subjects:
The Immunological System. B-lymphocytes and its receptors. T-lymphocytes. The complement system. The Major Histocompatibility Complex. Immunological reaction and inflammation. Immunological hypersensitivity mechanisms. Immunodeficiencies. Oral Immunopathology.

Main Bibliography

Immunology. Roitt, Brostoff, Male eds. 5th edition; (1)
1998 Mosby International, ISBN O723429189

Oral diseases. In: medical Immunology. Stites, eds. 9th edition (1)
1997 Appleton / lange. (McGraw-Hill Portugal)

Mucosal Immunology. Ogra, Pearay L et al, eds. 2nd Edition.
1999 Academic Press (2)

(1)Available at the Immunology Department
(2)Available at the Library of the FMDUP

Teaching methods and learning activities

Teaching and learning methods:
Theoretical classes are taught by the head of the department with the support of iconographic media (slides); after each theoretical subject lecture summaries are published. Theoretical-practical classes require a more direct cooperation of students, who should prepare in advance the subjects to be discussed (following a script and sometimes specific bibliography for some subjects) and cooperate in their presentation. Over the academic year students should prepare a written report on one of the theoretical-practical subjects presented, including a personal bibliographic research on a field previously selected by the teaching staff.

Evaluation Type

Evaluation with final exam

Eligibility for exams

The students with final classification ranging between 10 and 17 are readily passed, but can still do the complementary oral exam to improve the average. The students who obtain scores higher than 17 (18 to 20), have to do a final oral exam to improve the classification. The students with classifications ranging between 8.0 and 9.4 in the final written exam must have a compulsory oral exam. This is performed by a jury of 2 professors who will question the students for a maximum period of 30 minutes; the mark obtained in this exam is final and replaces the score on the written exam.

Calculation formula of final grade

To the classification obtained in the final written exam or from the arithmetical mean of the two written exams by frequency trials, and if higher than 9.5, a correction factor is added based on elements gathered in the seminars (information from the Teaching staff and the assessment of one of the written projects) with a maximum of 1.0 and a total of 17.4.

Examinations or Special Assignments

seminars

Classification improvement

Complementary oral exam to improve the average.

Observations

Teaching staff:


Luís Delgado, MD, PhD (Associate Professor, Department of Imunology , Faculty of Medicine, University of Oporto)