Chloride-selective membrane electrodes and optodes based on an indium(III) porphyrin for the determination of chloride in a sequential injection analysis system

• Type: Article in International Scientific Journal
• Date: 2004

Authors

Pimenta, AM (Author) Other; Araujo, AN (Author) FFUP; Conceicao, M (Author) FFUP; Montenegro, BSM (Author) Other; Pasquini, C (Author) Other; Rohwedder, JJR (Author) Other; Raimundo, IM (Author) Other

Journal

Title: Journal of Pharmaceutical and Biomedical Analysis

Vol. 36 No. 4

Pages: 49-55

ISSN: 0731-7085

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 35 Citations

ISI Web of Science

Scopus - 35 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

CORDIS: Health sciences

Other information

Authenticus ID: P-000-8GG

DOI: 10.1016/j.jpba.2004.04.011

Resumo (PT): Two quasi-independent methods for potentiometric and optical determination of chloride were simultaneously implemented in a flow system, providing real-time assessment of the quality of results. A potentiometric and an optical polymeric membrane doped with the same indium(III) octaethyl-porphyrin were used as sensor ionophore. The working mechanism and the analytical characteristics of these porphyrin-based sensors with respect to dynamic range, selectivity, repeatability and lifetime are discussed. These sensors, utilised as detectors in a flow system, were applied for the analysis of chloride in pharmaceutical solutions. The quality of the results obtained was evaluated by comparison with those provided by the reference method and no significant statistical differences at the 95% confidence level were observed. The simultaneous attainment of two measurements permitted the standardisation of results in real time and the detection of failures in the procedure. <br> <br> Keywords: Sequential injection analysis; Real-time accuracy assessment; Chloride-selective electrode; Chloride optode; Indium(III) octaethyl-porphyrin <br> <a target="_blank" href="http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TGX-4CS4RPC-1&_user=2460038&_coverDate=09%2F21%2F2004&_rdoc=8&_fmt=high&_orig=browse&_srch=doc-info(%23toc%235266%232004%23999639998%23519092%23FLA%23display%23Volume)&_cdi=5266&_sort=d&_docanchor=&_ct=34&_acct=C000057398&_version=1&_urlVersion=0&_userid=2460038&md5=639ebdeadb5a63fd9c60a9a8583334dd"> Texto integral</a> <br> <br>

Abstract (EN): Two quasi-independent methods for potentiometric and optical determination of chloride were simultaneously implemented in a flow system, providing real-time assessment of the quality of results. A potentiometric and an optical polymeric membrane doped with the same indium(III) octaethyl-porphyrin were used as sensor ionophore. The working mechanism and the analytical characteristics of these porphyrin-based sensors with respect to dynamic range, selectivity, repeatability and lifetime are discussed. These sensors, utilised as detectors in a flow system, were applied for the analysis of chloride in pharmaceutical solutions. The quality of the results obtained was evaluated by comparison with those provided by the reference method and no significant statistical differences at the 95% confidence level were observed. The simultaneous attainment of two measurements permitted the standardisation of results in real time and the detection of failures in the procedure.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7