Interaction between atypical microorganisms and E. coli in catheter-associated urinary tract biofilms

• Type: Article in International Scientific Journal
• Date: 2014

Authors

Andreia S. Azevedo (Author) Other; Carina Almeida (Author) Other; Luís F. Melo (Author) FEUP; Nuno F. Azevedo (Author) FEUP

Journal

Title: Biofouling

Vol. 30 No. 8

Pages: 893-902

ISSN: 0892-7014

Publisher: Taylor & Francis

Indexing

ISI Web of Knowledge - 16 Citations

ISI Web of Science

Scopus - 18 Citations

Scientific classification

FOS: Natural sciences > Biological sciences

Associated Projects

DNA mimics - Desenvolvimento e aplicação de mímicos de DNA para a rápida identificação de microrganismos patogénicos

Other information

Authenticus ID: P-009-WNA

DOI: 10.1080/08927014.2014.944173

Abstract (EN): Most biofilms involved in catheter-associated urinary tract infections (CAUTIs) are polymicrobial, with disease causing (eg Escherichia coli) and atypical microorganisms (eg Delftia tsuruhatensis) frequently inhabiting the same catheter. Nevertheless, there is a lack of knowledge about the role of atypical microorganisms. Here, single and dual-species biofilms consisting of E. coli and atypical bacteria (D. tsuruhatensis and Achromobacter xylosoxidans), were evaluated. All species were good biofilm producers (Log 5.84-7.25 CFU cm(-2) at 192 h) in artificial urine. The ability of atypical species to form a biofilm appeared to be hampered by the presence of E. coli. Additionally, when E. coli was added to a pre-formed biofilm of the atypical species, it seemed to take advantage of the first colonizers to accelerate adhesion, even when added at lower concentrations. The results suggest a greater ability of E. coli to form biofilms in conditions mimicking the CAUTIs, whatever the pre-existing microbiota and the inoculum concentration.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 10