Metallo-beta-lactamases as emerging resistance determinants in Gram-negative pathogens: open issues

• Type: Another Publication in an International Scientific Journal
• Date: 2007

Authors

Giuseppe Cornaglia (Author) Other; Murat Akova (Author) Other; Gianfranco Amicosante (Author) Other; Rafael Canton (Author) Other; Roberto Cauda (Author) Other; Jean Denis Docquier (Author) Other; Mikhail Edelstein (Author) Other; Jean Marie Frere (Author) Other; Miklos Fuzi (Author) Other; Moreno Galleni (Author) Other; Helen Giamarellou (Author) Other; Marek Gniadkowski (Author) Other; Raffaella Koncan (Author) Other; Balazs Libisch (Author) Other; Francesco Luzzaro (Author) Other; Vivi Miriagou (Author) Other; Ferran Navarro (Author) Other; Patrice Nordmann (Author) Other; Laura Pagani (Author) Other; Luisa Peixe (Author) FFUP; Laurent Poirel (Author) Other; Maria Souli (Author) Other; Evelina Tacconelli (Author) Other; Alkiviadis Vatopoulos (Author) Other; Gian Maria Rossolini (Author) Other

Journal

Title: International Journal of Antimicrobial Agents

Vol. 29 No. 4

Pages: 380-388

ISSN: 0924-8579

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 111 Citations

Scopus - 137 Citations

Scientific classification

FOS: Medical and Health sciences > Health sciences

Other information

Authenticus ID: P-004-AX8

DOI: 10.1016/j.ijantimicag.2006.10.008

Abstract (EN): The rapid spread of acquired metallo-beta-lactamases (MBLs) among major Gram-negative pathogens is a matter of particular concern worldwide and primarily in Europe, one of first continents where the emergence of acquired MBLs has been reported and possibly the geographical area where the increasing diversity of these enzymes and the number of bacterial species affected are most impressive. This spread has not been paralleled by accuracy/standardisation of detection methods, completeness of epidemiological knowledge or a clear understanding of what MBL production entails in terms of clinical impact, hospital infection control and antimicrobial chemotherapy. A number of European experts in the field met to review the current knowledge on this phenomenon, to point out open issues and to reinforce and relate to one another the existing activities set forth by research institutes, scientific societies and European Union-driven networks.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9