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Evaluate the impact of interventions to improve adherence and prevent / mitigate fragility and develop tools to evaluate the implementation of technological solutions in the elderly.


Active and healthy Ageing

Develop and evaluation of solutions to promote active and healthy ageing, assist older people to maintain independence, promote quality of life and ensure active participation in society. All activities were developed in an interdisciplinary way, and are focalized on adherence, frailty, and on technology for elderly.

Adherence

Non-adherence to medication is recognized as a worldwide public health problem with important implications for the management of chronic diseases, which affects every level of the population, particularly older adults due to the high number of coexisting diseases and consequent polypharmacy.

Estimated rates of adherence to long-term medication regimen are of about 50%, and there is no evidence for significant changes in the past 50 years. The consequences of non-adherence include poor clinical outcomes, increased morbidity and mortality and unnecessary healthcare costs.

In this field we are developing the following activities:
  • Review and develop new tools to measure adherence;
  • Evaluate the prevalence of non-adherence and its associated variables, in different diseases and countries;
  • Evaluate the prevalence of polypharmacy and its associated variables;
  • Evaluation of the socio-economic impact of non-adherence;
  • Development of educational programs to help health care professional to manage adherence and polypharmacy;
  • Big data analysis.

Relevant publications

  • Cognitive performance in older adults across Europe based on the SHARE database Aging, Neuropsychology, and Cognition.
    Rui Barbosa, Luís Midão, Marta Almada & Elísio Costa
    DOI: 10.1080/13825585.2020.1799927

  • The need for patient adherence standard measures for Big Data.
    Przemyslaw Kardas, Isabel Aguilar-Palacio, Marta Almada,..., E. Costa,..L. Midão,...,Bernard Vrijens. Journal of Medical Internet Research; 2020
    DOI: 10.2196/18150

  • Midão L, Giardini A, Menditto E, Kardas P, Costa E.
    Polypharmacy prevalence among older adults based on the survey of health, ageing and retirement in Europe.
    Arch Gerontol Geriatr;78:213-220. 2018

Frailty

Frailty is a geriatric multidimensional syndrome whose signs and symptoms are predictors of increased vulnerability to minor stress events, and the risk for adverse outcomes, such as falls, fractures, hospitalization, disability and death.

In this field we are developing the following activities:
  • Evaluation its prevalence using different tools;
  • Search for new associated variables;
  • Design and evaluation of intervention to prevent and mitigate frailty.

Relevant publications

  • Prevalence of fall and associated factors among community-dwelling European older adults: a cross-sectional study.
    M. Almada, P. Brochado, D. Portela, L. Midão, E. Costa.
    The Journal of Frailty & Aging 2020 (in press).

  • Prevalence of frailty status among the European elderly population: Findings from the Survey of Health, Aging and Retirement in Europe.
    Giulia Manfredi, Luís Midão, Constança Paúl, Clara Cena, Mafalda Duarte, Elísio Costa.
    Geriatr Gerontol Int. Aug;19(8):723-729. 2019
    doi: 10.1111/ggi.13689

  • Cardiovascular risk factors are correlated with decreased cognitive function among older adults across Europe based on the SHARE database.
    Lourenço J, Serrano A, Santos-Silva A, Gomes M, Afonso C, Freitas P, Paúl C, Costa E.
    Aging and Disease; 9(1): 90-101. 2018

Technology and ageing

E-health and m-health can be any kind of electronic device or monitoring system that is applied by health care professionals or by individuals to monitor or improve their health status. E-health typically refers to on-line and off-line computer-based applications while m-health refers to applications for mobile phones. Such tools can be used to stimulate a positive health behaviour change or assist persons to lead a healthier life style, or to support diagnosis and treatment of diseases. Moreover, both eHealth and mHealth are becoming prominent components of health and social care.

In this field we are developing the following activities:
  • Development of innovative solutions for health and social care;
  • Validation of new ICT solutions;
  • Development of ICT older adults’ empowerment educational programs.

Relevant publications

  • ARIA Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology.
    Bousquet J, Hellings PW, Agache I, Amat F, Annesi-Maesano I,… Costa E, …Zidarn M, Zuberbier T.
    J Allergy Clin Immunol 2018: S0091-6749(18)31359-9.

  • Geolocation with respect to personal privacy for the Allergy Diary app - A MASK study.
    Samreth D, Arnavielhe S, Ingenrieth F, …, Costa E, … , Poncelet P.
    World Allergy Organization Journal 2018;11:15.

  • Transfer of innovation on allergic rhinitis and asthma multimorbidity in the elderly (MACVIA-ARIA) - Reference Site Twinning (EIP on AHA).
    Bousquet J, Agache I, Aliberti MR, …, Costa E, … Oliviera B, Senn A.
    Allergy 2018;73(1):77-92.



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