Hemodynamics studies in 3D artery model from real CT scan

• Type: Article in International Conference Proceedings Book
• Date: 2013

Authors

Erica Doutel (Author) FEUP; Sónia Pinto (Author) FEUP; João Campos (Author) FEUP; João Miranda (Author) FEUP

Conference proceedings International

Title: ESB 2013 - 19th Congress of the European Society of Biomechanics

ESB 2013 - 19th Congress of the European Society of Biomechanics

Patras, Greece, 25-28th August 2013

Indexing

Scopus

Scientific classification

FOS: Engineering and technology > Mechanical engineering

CORDIS: Technological sciences > Engineering > Mechanical engineering

Other information

DOI: 10.1016/s0140- 6736(96)07493-4

Abstract (EN): Cardiovascular diseases are presently the leading cause of death in humans (Murray and Lopez 1997). From clinical practice, it is known that specific sites in the human circulatory system are particularly sensitive to the development of cardiovascular diseases. Fluid dynamics studies have been used to improve the knowledge of cardiovascular diseases. Experimental in vitro flow studies require theconstruction of a model of the blood vessel under study. To measure the flow through optical techniques, the model must be transparent in the wavelength of the light used and its half thickness must be smaller than the focal distance of the objective. In this work, a multi stage approach was developed to create 3D artery models from real CT scans in the millimetre-scale range, with or without stenosis, using melted sucrose as casting material. This method allows us to produce transparent non-contaminated PDMS channels suitable for flow visualizations and optical flow measurements. In parallel, the CT scans are processed to generate a computational mesh for hemodynamic simulation.

Language: English

Type (Professor's evaluation): Scientific