45S5 Bioglass-Derived Glass-Ceramic Scaffolds Containing Niobium Obtained by Gelcasting Method

• Type: Article in International Scientific Journal
• Date: 2021

Authors

de Siqueira, L (Author) Other; Liliana Grenho (Author) FMDUP; Fernandes, MH (Author) Other; Fernando Mendes Monteiro (Author) FEUP; Triches, ES (Author) Other

Journal

Title: Materials Research

Vol. 24

ISSN: 1516-1439

Publisher: Universidade Federal de Sao Carlos

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Other information

Authenticus ID: P-00T-KRA

DOI: 10.1590/1980-5373-mr-2020-0403

Abstract (EN): Scaffolds of bioglass derived from BG45S5 (45 wt% SiO2, 24.5 wt% CaO, 24.5 wt% Na2O and 6 wt% P2O5) containing 10 wt% niobium were prepared by gelcasting method. The scaffolds presented a 3D porous structure with interconnected and spherical pores (pore size range 100 mu m to 500 mu m) and high porosity (89%), similar to trabecular architecture of spongy bone. The compressive strength was 0.18 +/- 0.03 MPa which is acceptable for bone repair applications. The in vitro biological studies showed cytocompatibility for human osteoblastic cells as well tendency for higher alkaline phosphatase activity. Therefore, the findings here suggest the great potential of the scaffolds for using in bone tissue engineering.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6