Causality assessment in pharmacovigilance: principles and fundamentals of causal inference

• Type: Another Publication in a National Scientific Journal
• Date: 2022

Authors

Ferreira da Silva, RI (Author) FMUP

Journal

Title: Revista Científica da Rede Académica das Ciências da Saúde da Lusofonia

ISSN: 2184-4860

Publisher: Rede Académica das Ciências da Saúde da Lusofonia (RACS)

Other information

Authenticus ID: P-00X-3T7

DOI: 10.51126/revsalus.v4i2.466

Abstract (EN): <jats:p>Causality (or causal inference) has been a topic of intense debate among philosophers, epidemiologists, statisticians, and other clinical scientists. In pharmacovigilance, as in many other situations, there is not just one possible cause for an effect, but several. Causality imputation aims, through its own methodologies, to assess the nature of the relationship between a suspected adverse reaction and a particular drug or health product, seeking to establish the existence (or absence) and robustness of a causal link. This article focuses on a reflection on the importance of applying the principles and fundamentals of causal inference to pharmacovigilance, fundamental to the scientific rigor of an area governed by the difficulty of controlling for the unknown.</jats:p>

Language: English

Type (Professor's evaluation): Scientific