Uniaxial mechanical behavior of the human female bladder

• Type: Article in International Scientific Journal
• Date: 2011

Authors

Pedro A L S Martins (Author) Other; Agnaldo Lopes Silva Filho (Author) Other; Andrea Moura R M Rodrigues Maciel Fonseca (Author) Other; Agostinho Santos (Author) Other; Liliana Santos (Author) Other; Teresa Mascarenhas (Author) FMUP; Renato M N Natal Jorge (Author) FEUP; Antonio J M Ferreira (Author) FEUP

Journal

Title: International Urogynecology Journal

Vol. 22 No. Suppl. 1

Pages: 991-995

ISSN: 0937-3462

Indexing

ISI Web of Knowledge - 44 Citations

ISI Web of Science

Scopus - 43 Citations

Pubmed / Medline

Scientific classification

FOS: Medical and Health sciences > Clinical medicine

CORDIS: Technological sciences > Engineering > Biomedical enginnering

Other information

Authenticus ID: P-002-P1F

DOI: 10.1007/s00192-011-1409-0

Abstract (EN): Introduction and hypothesis The objective of the present study was to investigate the tensile biomechanical properties of the human female bladder. Methods Tissue samples were obtained from 13 cadavers without pelvic floor dysfunctions. We performed uniaxial tensile tests to measure the stiffness and maximum stress of the bladder tissue. Correlations were calculated using the Pearson correlation coefficient. Results The bladder tissue stiffness ranged from 1 to 4.1 MPa (mean stiffness, 1.9 +/- 0.2 MPa) and the maximum stress ranged from 0.5 to 2.6 MPa (mean maximum stress, 0.9 +/- 0.1 MPa). There was a strong positive correlation between stiffness and maximum stress in the bladder tissue (rho=0.829, p<0.001). Tissue from women younger than 50 years presented higher bladder stiffness than did tissue from older subjects (2.1 +/- 0.2 versus 1.3 +/- 0.1 MPa, p=0.02). Maximum bladder stress, however, was not associated with age (1.0 +/- 0.2 versus 0.7 +/- 0.1 MPa, p=0.349). In addition, body mass index and menopausal status were not associated with these biomechanical properties. Conclusions Age may influence the uniaxial mechanical behavior of the human female bladder.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5