Reversible parkinsonism due to a large intracranial tumour

• Type: Article in International Scientific Journal
• Date: 2012

Authors

Rocha, H (Author) Other; Cerejo, A (Author) Other; Garrett, MC (Author) FMUP; Massano, J (Author) Other

Journal

Title: BMJ Case Reports

Vol. 2012

ISSN: 1757-790X

Publisher: BMJ PUBLISHING GROUP

Indexing

ISI Web of Knowledge

Scopus - 4 Citations

Other information

Authenticus ID: P-008-8S9

DOI: 10.1136/bcr-2012-007823

Abstract (EN): A 77-year-old woman presented with progressively worsening apathy, depression, urinary incontinence and slowness of movement for the past 1 year. Asymmetric akinetic-rigid parkinsonism and mild left-sided hyperreflexia were seen on examination. No ocular movement impairment, cerebellar or sensory signs were noticed. Routine laboratory testing was normal. Brain imaging revealed a large frontal tumour which was subsequently excised and pathologically confirmed as a meningioma. Marked clinical improvement was documented 3 months after surgery, and persistent clinical and imaging remission have been confirmed annually for the following 3 years. There have been some reports of parkinsonism associated with intracranial tumours. Although this is probably an uncommon situation, it is potentially treatable, and symptoms might even remit completely following successful management. Parkinson's disease is a common cause of parkinsonism, but alternative aetiologies should be suspected whenever atypical findings are demonstrated by clinical history or examination. Copyright 2012 BMJ Publishing Group. All rights reserved.

Language: English

Type (Professor's evaluation): Scientific