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Presence of Antibodies against Genogroup VI Norovirus in Humans

Title
Presence of Antibodies against Genogroup VI Norovirus in Humans
Type
Article in International Scientific Journal
Year
2013
Authors
Joao Rodrigo Mesquita
(Author)
Other
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Veronica P Costantini
(Author)
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Jennifer L Cannon
(Author)
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Seh ching Lin
(Author)
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Jan Vinje
(Author)
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Journal
Title: Virology JournalImported from Authenticus Search for Journal Publications
Vol. 10
Final page: 176
ISSN: 1743-422X
Publisher: Springer Nature
Scientific classification
FOS: Natural sciences > Biological sciences
Other information
Authenticus ID: P-005-02S
Abstract (EN): Background: Noroviruses are important enteric pathogens in humans and animals. Recently, we reported a novel canine norovirus (CaNoV) in dogs with diarrhea belonging to a new genogroup (GVI). No data are available on exposure of humans to this virus. Methods: Sera from 373 small animal veterinarians and 120 age-matched population controls were tested for IgG antibodies to CaNoV by a recombinant virus like particle based enzyme-linked immunosorbent assay. Results: Antibodies to CaNoV were found in 22.3% of the veterinarians and 5.8% of the control group (p<0.001). Mean corrected OD450 values for CaNoV antibodies were significantly higher in small animal veterinarians compared to the control group. Conclusions: These findings suggest that CaNoV may infect humans and small animal veterinarians are at an increased risk for exposure to this virus. Additional studies are needed to assess if this virus is able to cause disease in humans.
Language: English
Type (Professor's evaluation): Scientific
Contact: ahx8@cdc.gov
No. of pages: 5
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