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Bioactive diterpenoids, a new jatrophane and two ent-abietanes, and other constituents from Euphorbia pubescens

Title
Bioactive diterpenoids, a new jatrophane and two ent-abietanes, and other constituents from Euphorbia pubescens
Type
Article in International Scientific Journal
Year
2004
Authors
Valente, C
(Author)
Other
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Pedro, M
(Author)
Other
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Duarte, A
(Author)
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Nascimento, MSJ
(Author)
FFUP
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Abreu, PM
(Author)
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Ferreira, MJU
(Author)
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Journal
Vol. 67
Pages: 902-904
ISSN: 0163-3864
Scientific classification
FOS: Medical and Health sciences > Basic medicine
Other information
Authenticus ID: P-000-AMR
Abstract (EN): A new jatrophane diterpene, pubescenol (1), known ent-abietane lactones, helioscopinolide A (2) and B (3), and taraxerone, 24-methylenecycloartanol, and vanillin have been isolated from Euphorbia pubescens. Diterpenes 1-3 and previously described pubescene D (4) were shown to be moderate inhibitors of the growth of MCF-7, NCI-H460, and SF-268 human tumor cell lines, whereas compounds 2 and 3 also exhibited significant antibacterial activity against Staphylococcus aureus.
Language: English
Type (Professor's evaluation): Scientific
Contact: mjuferreira@ff.ul.pt
No. of pages: 3
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