Optimal time for constant drug infusion initialization in neuromuscular blockade control

• Type: Article in International Conference Proceedings Book
• Date: 2014

Authors

Angela Miranda (Author) Other; Teresa Mendonca (Author) FCUP; Rocha, P (Author) FEUP

Conference proceedings International

Title: 2014 IEEE INTERNATIONAL SYMPOSIUM ON MEDICAL MEASUREMENTS AND APPLICATIONS (MEMEA)

Pages: 258-263

9th IEEE International Symposium on Medical Measurements and Applications (IEEE MeMeA)

Lisbon, PORTUGAL, JUN 11-12, 2014

Indexing

ISI Web of Knowledge - 1 Citation

Scopus - 2 Citations

Scientific classification

FOS: Engineering and technology > Environmental biotechnology

Other information

Authenticus ID: P-009-TDC

DOI: 10.1109/memea.2014.6860068

Abstract (EN): This paper presents a control strategy for neuromuscular blockade (NMB) level, in order to determine the optimal time to initialize the administration of the muscle relaxant rocuronium by means of the continuous infusion of a constant dose. The constant value of muscle relaxant for a particular patient undergoing general anesthesia is computed in order to guarantee that the steady-state value of neuromuscular blockade level is the desired reference value. In order to apply this open-loop control strategy, the patient's NMB response to rocuronium is assumed to be modeled by a recently proposed parameter parsimonious model.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6