Self-calibrating total-mass controller for the neuromuscular blockade matching the anesthesiologists' mindset

• Type: Article in International Conference Proceedings Book
• Date: 2013

Authors

Luis A Paz (Author) Other; Margarida M Silva (Author) Other; Simao Esteves (Author) Other; Teresa Mendonca (Author) FCUP

Conference proceedings International

Title: 2013 21ST MEDITERRANEAN CONFERENCE ON CONTROL AND AUTOMATION (MED)

Pages: 723-728

21st Mediterranean Conference on Control and Automation (MED)

Platanias, GREECE, JUN 25-28, 2013

Indexing

ISI Web of Knowledge - 2 Citations

Scopus - 4 Citations

Scientific classification

FOS: Engineering and technology > Electrical engineering, Electronic engineering, Information engineering

Other information

Authenticus ID: P-008-EXY

DOI: 10.1109/med.2013.6608803

Abstract (EN): A self-calibrating total-mass controller for the neuromuscular blockade (NMB) based on the minimally parameterized parsimonious (MPP) Wiener model is presented. Using input-output data collected from the initial bolus administration until recovery, the parameters of the MPP model that are used for the controller design are chosen from a set of fifty realistic models for the effect of the muscle relaxant rocuronium in the NMB. In order to overcome modeling uncertainties a numeric self-calibration of the parameters in the MPP model nonlinearity was implemented. This step matches the anesthesiologists' mindset. The controller was extensively tested in simulation and in real cases. The good reference tracking results show the reliability of the proposed strategy and supports its use in the clinical practice.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6