A Simple Model for the Identification of Drug Effects

• Type: Article in International Conference Proceedings Book
• Date: 2009

Authors

Hugo Alonso (Author) FEUP; Teresa Mendonca (Author) FCUP; Joao M Lemos (Author) Other; Torbjorm Wigren (Author) Other

Conference proceedings International

Title: WISP 2009: 6TH IEEE INTERNATIONAL SYMPOSIUM ON INTELLIGENT SIGNAL PROCESSING, PROCEEDINGS

Pages: 269-273

6th IEEE International Symposium on Intelligent Signal Processing

Budapest, HUNGARY, AUG 26-28, 2009

Indexing

ISI Web of Knowledge - 6 Citations

Scopus - 7 Citations

Scientific classification

FOS: Engineering and technology > Electrical engineering, Electronic engineering, Information engineering

Other information

Authenticus ID: P-003-SDE

DOI: 10.1109/wisp.2009.5286552

Abstract (EN): This paper presents a new model for the identification of drug effects. The main advantage of this model over standard models is its simplicity. In fact, the proposed model establishes an affine relation between the drug infusion rate and the corresponding effect on the patient where there are few parameters to estimate, while standard models usually assume a nonlinear relation with many parameters to estimate. Furthermore, it is shown that the new model has a good ability to describe real data. Here, the case study focuses on the muscle relaxant atracurium and its influence on the neuromuscular blockade, but other drugs such as the hypnotic propofol and the analgesic remifentanil and their influence on the depth of anaesthesia may also be considered.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5