Trilinear PARAFAC decomposition of synchronous fluorescence spectra of mixtures of the major metabolites of acetylsalicylic acid

• Type: Article in International Scientific Journal
• Date: 1998

Authors

da Silva, JCGE (Author) FCUP; Novais, SAG (Author) Other

Journal

Title: The Analyst

Vol. 123

Pages: 2067-2070

ISSN: 0003-2654

Publisher: Royal Society of Chemistry

Indexing

ISI Web of Knowledge - 20 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

Other information

Authenticus ID: P-001-6YC

DOI: 10.1039/a802690d

Abstract (EN): Mixtures of the three major metabolites of acetylsalicylic acid (salicylic, gentisic and salicyluric acid) were analyzed by synchronous molecular fluorescence spectroscopy. Three-way data matrices were generated by acquisition of spectra as a function bf the pH (between 2 and 11) and of different relative concentrations of the three components. The PARAFAC trilinear model, without restrictions and using one factor per metabolite, was used in the data analysis. A full decomposition of the data matrices into the spectra, concentration and pH profiles was obtained. This result shows that molecular fluorescence spectroscopy can be used for the development of robust analytical methods for th simultaneous determination of the three major metabolites of acetylsalicylic acid in complex background samples.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4