Sequence variation at three X chromosomal short tandem repeats in Caucasian and African populations

• Type: Article in International Scientific Journal
• Date: 2008

Authors

Gomes, I (Author) Other; Prinz, M (Author) Other; Pereira, R (Author) Other; Bieschke, E (Author) Other; Amorim, A (Author) FCUP; Carracedo, A (Author) Other; Gusmao, L (Author) Other

Journal

Title: Forensic Science International: Genetics Supplement Series

Vol. 1 No. 1

Pages: 147-149

ISSN: 1875-1768

Publisher: Elsevier

Indexing

ISI Web of Knowledge

Scopus - 2 Citations

Other information

Authenticus ID: P-007-N2X

DOI: 10.1016/j.fsigss.2007.10.097

Abstract (EN): Sequence variation for the X chromosome short tandem repeats (X-STRs) DXS9898, DXS6789 and GATA172D05 was studied in two major population groups, namely Caucasians and Africans. DXS6789 revealed two different subtype sequence polymorphisms: for shorter alleles, with less than 17 repeats, results showed a simple composition with the following structure: (TATG)m-(TATC)n. For longer alleles, a constant TATC insertion was observed at the beginning of the variable repeat unit. Additionally, alleles identical in size revealed structural variations regarding the TATG/TATC proportion. Africans showed a higher intra-allelic variation at this locus than the Caucasian population group. For all three loci, DXS9898, DXS6789 and GATA172D05, no unique structure was found among Africans and Caucasians.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3