Mitochondrial DNA variability in populations from East Timor (Timor Leste)

• Type: Article in International Scientific Journal
• Date: 2006

Authors

Souto, L (Author) Other; Rocha, AM (Author) Other; Pires, A (Author) Other; Ferreira, E (Author) Other; Kayser, M (Author) Other; Amorim, A (Author) FCUP; Corte Real, F (Author) Other; Vieira, DN (Author) Other

Journal

Title: International Congress Series

Vol. 1288

Pages: 115-117

ISSN: 0531-5131

Publisher: Elsevier B.V.

Indexing

ISI Web of Knowledge

Scopus - 2 Citations

Other information

Authenticus ID: P-007-FDQ

DOI: 10.1016/j.ics.2005.11.060

Abstract (EN): In this study we continue the genetic characterization of human populations from East Timor, as previously started for autosomal STRs and Y STRs, with a preliminary report on mitochondrial DNA (mtDNA) diversity. Individual samples (n = 133) collected from all the districts of East Timor and representing different linguistic groups were studied for the hypervariable region 1 (HVS1) sequence and the 9-bp deletion (intergenic region COII-tRNA lys). 57 haplotypes were found (haplotype diversity = 0.9727; nucleotide diversity=0.017864; mean number of pairwise differences = 7.52) and the 9 bp deletion reached 16.7%. We found typical sequences of non-Austronesian (Papuan) speaking populations from New Guinea, along with a significant frequency of haplogroup B (namely B4a). In addition our overall genetic data (mtDNA, STRs) may serve as a starting-point to create a genetic database for forensic applications in East Timor. © 2006.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3