Genetic analysis of autosomal and Y-specific STRs in the Karimojong population from Uganda

• Type: Article in International Scientific Journal
• Date: 2006

Authors

Gusmao, L (Author) Other; Sanchez Diz, P (Author) Other; Gomes, I (Author) Other; Alves, C (Author) Other; Carracedo, A (Author) Other; Joao Prata, M (Author) FCUP; Amorim, A (Author) FCUP

Journal

Title: International Congress Series

Vol. 1288

Pages: 213-215

ISSN: 0531-5131

Publisher: Elsevier B.V.

Indexing

ISI Web of Knowledge

Scopus - 6 Citations

Other information

Authenticus ID: P-007-FDF

DOI: 10.1016/j.ics.2005.09.129

Abstract (EN): In this work, 90 individuals living in Karamoja region were typed for 17 autosomal STRs and 40 males were also typed for 12 Y-STRs. Hardy-Weinberg equilibrium was tested for each autosomal locus and no deviations from equilibrium were observed. For autosomal STRs, our sample shows a combined matching probability of 1 in 6.5 × 1019 individuals and a combined power of exclusion of 0.999999988. Haplotype diversity for Y-STRs was 0.9859 and 32 different haplotypes were detected. Our sample was compared with available autosomal data from sub-Saharan African samples and significant differences were found with Mozambique; Cabinda (Angola); Equatorial Guinea; and with Rwanda. Comparisons with the Y-STR data, revealed large genetic distances between our sample and Mozambique, Cabinda and Equatorial Guinea.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3