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Online reference database of European Y-chromosomal short tandem repeat (STR) haplotypes

Title
Online reference database of European Y-chromosomal short tandem repeat (STR) haplotypes
Type
Article in International Scientific Journal
Year
2001
Authors
Roewer, L
(Author)
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Krawczak, M
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Willuweit, S
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Nagy, M
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Alves, C
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Amorim, A
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FCUP
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Anslinger, K
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Augustin, C
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Betz, A
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Bosch, E
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Caglia, A
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Carracedo, A
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Corach, D
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Dekairelle, AF
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Dobosz, T
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Dupuy, BM
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Furedi, S
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Gehrig, C
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Gusmao, L
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Henke, J
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Henke, L
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Hidding, M
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Hohoff, C
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Hoste, B
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Jobling, MA
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Kargel, HJ
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de Knijff, P
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Lessig, R
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Liebeherr, E
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Lorente, M
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Martinez Jarreta, B
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Nievas, P
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Nowak, M
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Parson, W
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Pascali, VL
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Penacino, G
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Ploski, R
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Rolf, B
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Sala, A
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Schmidt, U
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Schmitt, C
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Schneider, PM
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Szibor, R
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Teifel Greding, J
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Kayser, M
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Journal
Vol. 118
Pages: 106-113
ISSN: 0379-0738
Publisher: Elsevier
Scientific classification
FOS: Medical and Health sciences > Other medical sciences
Other information
Authenticus ID: P-000-VH1
Abstract (EN): The reference database of highly informative Y-chromosomal short tandem repeat (STR haplotypes (YHRD), available online at http://ystr.charite.de, represents the largest collection of male-specific genetic profiles currently available for European populations. By September 2000, YHRD contained 4688 9-locus (so-called "minimal") haplotypes, 40% of which have been extended further to include two additional loci. Establishment of YHRD has been facilitated by the joint efforts of 31 forensic and anthropological institutions. All contributing laboratories have agreed to standardize their Y-STR haplotyping protocols and to participate in a quality assurance exercise prior to the inclusion of any data. In view of its collaborative character, and in order to put YHRD to its intended use, viz, the support of forensic caseworkers in their routine decision-making process, the database has been made publicly available via the Internet in February 2000. Online searches for complete or partial Y-STR haplotypes from evidentiary or non-probative material can be performed on a non-commercial basis, and yield observed haplotype counts as well as extrapolated population frequency estimates. In addition, the YHRD website provides information about the quality control test, genotyping protocols, haplotype formats and informativity, population genetic analysis, literature references, and a list of contact addresses of the contributing laboratories.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 8
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