Genetic diversity of Y-specific STRs in chimpanzees (Pan troglodytes)

• Type: Article in International Scientific Journal
• Date: 2002

Authors

Gusmao, L (Author) Other; Gonzalez Neira, A (Author) Other; Alves, C (Author) Other; Sanchez Diz, P (Author) Other; Dauber, EM (Author) Other; Amorim, A (Author) FCUP; Carracedo, A (Author) Other

Journal

Title: American Journal of Primatology

Vol. 57

Pages: 21-29

ISSN: 0275-2565

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 10 Citations

Scopus - 10 Citations

Scientific classification

FOS: Natural sciences > Biological sciences

Other information

Authenticus ID: P-000-PCQ

DOI: 10.1002/ajp.1084

Abstract (EN): Using the primers described for humans, sequences for 11 Y-specific microsatellites (DYS434, DYS435, DYS436, DYS437, DYS438, DYS439, GATA A10, A7.1, A7.2, C4, and H4 [Gusmao et al., in press]), previously described in 10 male chimpanzees (Pan troglodytes), were confirmed in nine additional male chimpanzees. Sequences for nine additional microsatellites (DYS19, DYS385I and H, DYS389I and H, DYS390, DYS391, DYS392, and DYS393) were determined in all 19 male chimpanzees; homology to human Y-Short Tandem Repeat (STRs) was confirmed by sequencing. Good amplification results were not obtained for DYS19 and DYS385I/II. Two amplicons were obtained for DYS389I/II, but in contrast to humans, the larger fragment was not Y-specific. Moreover, no polymorphism was observed for DYS434, DYS435, or GATA A10. Consequently, these eight STRs were eliminated from further analyses, and haplotype and allele frequencies were estimated for the remaining 12 STRs. A high haplotype diversity value was found (1.000 +/- 0.017), demonstrating the usefulness and informative power of these Y-STRs for future studies on chimpanzee population genetics. (C) 2002 Wiley-Liss, Inc.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9