The Karimojong from Uganda: Genetic characterization using an X-STR decaplex system

• Type: Article in International Scientific Journal
• Date: 2009

Authors

Iva Gomes (Author) Other; Vania Pereira (Author) Other; Veronica Gomes (Author) Other; Maria Joao Prata (Author) FCUP; Nadia Pinto (Author) Other; Angel Carracedo (Author) Other; Antonio Amorim (Author) FCUP; Leonor Gusmao (Author) FCUP

Journal

Title: Forensic Science International: Genetics

Vol. 3

Pages: E127-E128

ISSN: 1872-4973

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 19 Citations

Scopus - 25 Citations

Scientific classification

FOS: Medical and Health sciences > Other medical sciences

Other information

Authenticus ID: P-003-G3V

DOI: 10.1016/j.fsigen.2008.10.009

Abstract (EN): The Karimojong, an African group from the Karamoja region of Northeast Uganda, were genetically analysed using a decaplex system for X chromosome short tandem repeats (X-STRs). A total of 255 individuals (117 males and 138 females) were genotyped for the following loci: DXS8378, DXS9898, DXS7133, GATA31E08, GATA172D05, DXS7423, DXS6809, DXS7132, DXS9902 and DXS6789. Allele frequencies and parameters for forensic evaluation were calculated for each STR. No association was found between any pairs of loci studied. DXS6789 was the most polymorphic marker in this sample, followed by DXS6809, with gene diversities of 84.79% and 83.94%, respectively. The less discriminating locus observed was DXS7133, with a gene diversity of 39.79%. High overall values of power of discrimination were obtained for female (1 in 1.8 x 1010) and male samples (1 in 1.6 x 106), as well as high power of exclusion in father/mother/daughter trios (99.9997%), in father daughter duos (99.9862%) and in half sisters with same father (99.0331%). These results confirm the potential of this 10-plex in parentage testing and in human identification.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 2