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Synthesis of luciferyl coenzyme A: A bioluminescent substrate for firefly luciferase in the presence of AMP

Title
Synthesis of luciferyl coenzyme A: A bioluminescent substrate for firefly luciferase in the presence of AMP
Type
Article in International Scientific Journal
Year
2005
Authors
Fraga, H
(Author)
Other
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Fontes, R
(Author)
FMUP
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da Silva, JCGE
(Author)
FCUP
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Journal
Vol. 44
Pages: 3427-3429
ISSN: 1433-7851
Publisher: Wiley-Blackwell
Scientific classification
FOS: Natural sciences > Chemical sciences
Other information
Authenticus ID: P-000-557
Abstract (EN): (Chemical Equation Presented) Shedding light on luciferase: Luciferyl coenzyme A (1) was synthesized and it was found that luciferase catalyzes light production from luciferyl coenzyme A and AMP. The results of this study open perspectives for new bioanalytical methods and are strong evidence for the evolutionary relationship between firefly luciferase and acyl-CoA synthetases. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.
Language: English
Type (Professor's evaluation): Scientific
Contact: jcsilva@fc.up.pt
No. of pages: 3
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