Detection of colon cancer by terahertz techniques

• Type: Article in International Scientific Journal
• Date: 2011

Authors

Faustino Wahaia (Author) Other; Gintaras Valusis (Author) Other; Luis M Bernardo (Author) Other; Abilio Almeida (Author) FCUP; Joaquim A Moreira (Author) FCUP; Patricia C Lopes (Author) Other; Jan Macutkevic (Author) Other; Irmantas Kasalynas (Author) Other; Dalius Seliuta (Author) Other; Ramunas Adomavicius (Author) Other; Rui Henrique (Author) ICBAS; Machado Lopes (Author) Other

Journal

Title: Journal of Molecular Structure

Vol. 1006

Pages: 77-82

ISSN: 0022-2860

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 74 Citations

Scopus - 78 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

Other information

Authenticus ID: P-002-HQP

DOI: 10.1016/j.molstruc.2011.05.049

Abstract (EN): Human normal and cancer affected samples of colon tissue have been measured using transmission time-domain terahertz spectroscopy and continuous wave terahertz imaging. We show that it is possible to distinguish between normal and cancerous regions in the samples when they a:e fixed in formalin or embedded in paraffin. The still noticeable contrast in the dried paraffin-embedded tissues could indicate that there are additional contrast-contributing factors other than water, which is the main goal of the present work. Plots of the refractive index of normal and cancer affected tissues as well as 2-D transmission THz images are shown. Experimental results are presented and the conditions for discrimination between normal and affected formalin-fixed and paraffin-embedded tissue are discussed.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6