Cytochemical detection of calcium in a case of calcinosis circumscripta in a dog

• Type: Article in International Scientific Journal
• Date: 2006

Authors

marcos, r (Author) Other; santos, m (Author) Other; oliveira, j (Author) Other; vieira, mj (Author) Other; vieira, al (Author) Other; rocha, e (Author) ICBAS

Journal

Title: Veterinary Clinical Pathology

Vol. 35

Pages: 239-242

ISSN: 0275-6382

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 8 Citations

Scopus - 12 Citations

Scientific classification

FOS: Agrarian Sciences > Veterinary science

Other information

Authenticus ID: P-004-KNV

DOI: 10.1111/j.1939-165x.2006.tb00122.x

Abstract (EN): A 9-month-old intact female Serra-da-Estrela dog (giant Portuguese breed) was presented with a 2-month history of lingual lesions. Two hard, nodular, nonpainful lesions were observed on the lateral border of the tongue. Fine-needle aspiration yielded a chalky white material. Hemacolor-stained smears showed an amorphous granular basophilic background with crystal-like structures and granulomatous inflammation consisting of foamy macrophages and giant cells. Cytochernical staining with von Kossa and Alizarin red S confirmed the calcareous nature of the material. The cytologic diagnosis was lingual calcinosis circumscripta; this was later confirmed by histopathologic examination. To our knowledge, this case is the first to document the use of von Kossa and Alizarin red S on cytologic smears to obtain a definitive diagnosis of lingual calcinosis circumscripta.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4