Protein translocation across the peroxisomal membrane

• Type: Another Publication in an International Scientific Journal
• Date: 2004

Authors

azevedo, je (Author) ICBAS; costa-rodrigues, j (Author) Other; guimaraes, cp (Author) Other; oliveira, me (Author) Other; sa-miranda, c (Author) Other

Journal

Title: Cell Biochemistry and Biophysics

Vol. 41

Pages: 451-468

ISSN: 1085-9195

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 22 Citations

Scopus - 23 Citations

Other information

Authenticus ID: P-000-CE7

DOI: 10.1385/cbb:41:3:451

Abstract (EN): Peroxisomal matrix proteins are synthesized on free cytosolic ribosomes and posttranslationally imported into the organelle. Translocation of these newly synthesized proteins across the peroxisomal membrane requires the concerted action of many different proteins, the majority of which were already identified. However, not much is known regarding the mechanism of protein translocation across this membrane system. Here, we discuss recent mechanistic and structural data. These results point to a model in which proteins en route to the peroxisomal matrix are translocated across the organelle membrane by their own receptor in a process that occurs through a large membrane protein assembly.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 18