Effects of resistance and aerobic exercise on physical function, bone mineral density, OPG and RANKL in older women

• Type: Article in International Scientific Journal
• Date: 2011

Authors

Elisa A Marques (Author) Other; Flavia Wanderley (Author) Other; Leandro Machado (Author) FADEUP; Filipa Sousa (Author) Other; Joao L Viana (Author) Other; Daniel Moreira Goncalves (Author) Other; Pedro Moreira (Author) FCNAUP; Jorge Mota (Author) FADEUP; Joana Carvalho (Author) FADEUP

Journal

Title: Experimental Gerontology

Vol. 46 No. 7

Pages: 524-532

ISSN: 0531-5565

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 67 Citations

ISI Web of Science

Scopus - 96 Citations

Scientific classification

FOS: Medical and Health sciences > Clinical medicine

CORDIS: Health sciences

Other information

Authenticus ID: P-002-Q6E

DOI: 10.1016/j.exger.2011.02.005

Abstract (EN): This study compared the effects of a resistance training protocol and a moderate-impact aerobic training protocol on bone mineral density (BMD), physical ability, serum osteoprotegerin (OPG), and receptor activator of nuclear factor kappa B ligand (RANKL) levels. Seventy-one older women were randomly assigned to resistance exercise (RE), aerobic exercise (AE) or a control group (CON). Both interventions were conducted 3 times per week for 8 months. Outcome measures included proximal femur BMD, muscle strength, balance, body composition, serum OPG, and RANKL levels. Potential confounding variables included dietary intake, accelerometer-based physical activity (PA), and molecularly defined lactase nonpersistence. After 8 months, only RE group exhibited increases in BMD at the trochanter (2.9%) and total hip (1.5%), and improved body composition. Both RE and AE groups improved balance. No significant changes were observed in OPG and RANKL levels, and OPG/RANKL ratio. Lactase nonpersistence was not associated with BMD changes. No group differences were observed in baseline values or change in dietary intakes and daily PA. Data suggest that 8 months of RE may be more effective than AE for inducing favourable changes in BMD and muscle strength, whilst both interventions demonstrate to protect against the functional balance control that is strongly related to fall risk.

Language: English

Type (Professor's evaluation): Scientific

Notes: <a href="http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS&DestLinkType=FullRecord&KeyUT=000292181700002">Indexado na ISI Web of Science</a>

No. of pages: 9