Production of porous hydroxyapatite with potential for controlled drug delivery

• Type: Article in International Scientific Journal
• Date: 2004

Authors

A. C. Queiróz (Author) Other; S. Teixeira (Author) Other; José D. Santos (Author) FEUP; Fernando J. Monteiro (Author) FEUP

Journal

Title: Materials Science Forum

Vol. 455-456

Pages: 358-360

ISSN: 0255-5476

Publisher: Trans Tech Publications Ltd

Indexing

ISI Web of Science

Scientific classification

FOS: Engineering and technology > Materials engineering

CORDIS: Technological sciences > Engineering > Biomaterial engineering

Other information

DOI: 10.4028/www.scientific.net/MSF.455-456.358

Abstract (EN): Porous hydroxyapatite was prepared in order to be used as a drug carrier and promote bone ingrowth. For this purpose, the microstructure should have interconnective pores and micro as well as macro porosity, for bone cell adhesion and bone ingrowth. The porous hydroxyapatite prepared by the burn-out method exhibits all these features. For measuring porosity, SEM analysis, mercury intrusion porosimetry and BET were used. FT-IR and XRD analysis revealed that only hydroxyapatite phase was present, being this result similar to the one found for dense samples. The morphology obtained appears to be well adapted to bone growth and drug adsorption.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3