Factors influencing differences between invasive and spontaneous baroreflex estimates: distinct methods or different data?

• Type: Article in International Conference Proceedings Book
• Date: 2011

Authors

Sonia Gouveia (Author) FCUP; Ana Paula Rocha (Author) FCUP; Philippe van de Borne (Author) Other; Pablo Laguna (Author) Other

Conference proceedings International

Title: 2011 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)

Pages: 2554-2557

33rd Annual International Conference of the IEEE Engineering-in-Medicine-and-Biology-Society (EMBS)

Boston, MA, AUG 30-SEP 03, 2011

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Scientific classification

FOS: Engineering and technology > Environmental biotechnology

Other information

Authenticus ID: P-002-WX0

DOI: 10.1109/iembs.2011.6090706

Abstract (EN): Currently invasive BRS estimates are obtained with drug-induced data assuming a sigmoidal SBP-RR relationship, while spontaneous BRS estimates are obtained with non-sigmoidal estimators. In particular, the events (sequences) technique provides a spontaneous BRS estimate based on baroreflex events, BEs (baroreflex sequences, BSs). In this work, BRS estimates are compared considering that can be obtained with different estimators and evaluated in different conditions. All BRS estimates were found to be significantly correlated. In comparison with BS estimates, BE estimates from spontaneous data exhibited higher correlation with sigmoidal estimates and their differences were associated with differences in SBP levels from invasive to spontaneous condition. BE estimator evaluated in different conditions decreased the differences between BRS estimates, pointing out differences due to the use of distinct methods, and such differences were correlated with differences in SBP and RR levels from invasive to spontaneous conditions. Finally, sigmoid estimates were more correlated with BE estimates in invasive data in comparison with those evaluated from BS. In conclusion, BRS analysis from BEs provides an estimate that exhibits higher correlation and lower differences between BRS estimates from different conditions, and reflects properly the BRS physiology.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4