Antioxidant phenolic esters with potential anticancer activity: A Raman spectroscopy study

• Type: Article in International Scientific Journal
• Date: 2008

Authors

calheiros, r. (Author) Other; machado, n. f. l. (Author) Other; fiuza, s. m. (Author) Other; gaspar, a. (Author) Other; garrido, j. (Author) Other; milhazes, n. (Author) Other; borges, f. (Author) FFUP; marques, m. p. m. (Author) Other

Journal

Title: Journal of Raman Spectroscopy

Vol. 39

Pages: 95-107

ISSN: 0377-0486

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 46 Citations

Scopus - 50 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

CORDIS: Physical sciences > Chemistry

Other information

Authenticus ID: P-004-3Y2

DOI: 10.1002/jrs.1822

Abstract (EN): A Raman study of hydroxycinnamic and hydroxybenzoic esters (caffeates, ferulates and gallates) displaying antioxidant and anticancer properties was undertaken, with particular emphasis on the analysis of the effect of the ring substituents and the nature of the ester alkyl chain on their spectroscopic features. A complete assignment of the spectra was carried out for all the compounds investigated, in the light of the corresponding calculated wavenumbers (at the density functional theory level). Distinct vibrational patterns were observed for each type of ester, thereby allowing their ready characterisation and identification by Raman spectroscopy. Evidence of the occurrence of intermolecular hydrogen bonds, leading to the formation of dimers in the condensed phase, was also obtained. Copyright (c) 2007 John Wiley & Sons, Ltd.

Language: English

Type (Professor's evaluation): Scientific