Synthesis of a New (+)-Catechin-Derived Compound: 8-Vinylcatechin

• Type: Article in International Scientific Journal
• Date: 2008

Authors

Luis Cruz (Author) Other; Enrique Borges (Author) FCUP; Artur M S Silva (Author) Other; Nuno Mateus (Author) FCUP; Victor de Freitas (Author) FCUP

Journal

Title: Letters in Organic Chemistry

Vol. 5

Pages: 530-536

ISSN: 1570-1786

Publisher: Bentham Science

Indexing

ISI Web of Knowledge - 19 Citations

Scopus - 19 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

Other information

Authenticus ID: P-003-VY7

DOI: 10.2174/157017808785982211

Abstract (EN): A strategy for the synthesis of 8-vinylcatechin was developed, which involves (+)-catechin silylation with TBDMS-Cl, followed by bromination with NBS, a cross-coupling Suzuki reaction with vinylboronic acid pinacol ester and cleavage of TBDMS groups with TBAF, affording the 8-vinylcatechin.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7