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Blocking the receptor for interleukin 10 protects mice from lethal listeriosis

Title
Blocking the receptor for interleukin 10 protects mice from lethal listeriosis
Type
Article in International Scientific Journal
Year
2001
Authors
Silva, RA
(Author)
Other
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Appelberg, R
(Author)
ICBAS
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Journal
Vol. 45
Pages: 1312-1314
ISSN: 0066-4804
Indexing
Pubmed / Medline
Scientific classification
FOS: Medical and Health sciences > Basic medicine
CORDIS: Health sciences > Medical sciences > Medicine > Infections
Other information
Authenticus ID: P-000-VWD
Abstract (EN): High doses of Listeria monocytogenes overcome the ability of a normal mouse to control the infection, due to massive bacterial replication. Treatment with an anti-interleukin 10 (IL-10) receptor monoclonal antibody prevented the fatal course of infection with high doses of bacteria. This work shows that blocking the receptor for IL-10 may have useful therapeutic applications.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 3
License type: Click to view license CC BY-NC
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2001(AAC), Silva & Appelberg 1581.02 KB
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