Right Ventricular Dysfunction in Dilated Cardiomyopathy: a Dim Outcome

• Type: Summary of Presentation in an International Conference
• Date: 2012

Authors

Paiva M (Author) Other; Amorim S (Author) Other; Alves E (Author) Other; Campelo M (Author) Other; Moura B (Author) Other; Viana P (Author) Other; Silva Cardoso J (Author) Other; Maciel MJ (Author) FMUP

Conference proceedings International

Title: European Journal of Heart Failure Supplements

Initial page: P257

Heart Failure Congress 2012

Belgrade, 2012

Scientific classification

FOS: Medical and Health sciences > Clinical medicine

Other information

Abstract (EN): Introduction: Morbidity and mortality have been shown to be higher in patients with right ventricular dysfunction. Methods: A transversal study was performed on a group of patients with dilated cardiomyopathy of all causes, for all-cause mortality and for occurrence of death or urgent transplantation. Patients were defined were to have or not right ventricular dysfunction (TAPSE≪16mm and/or S wave≪11m/s) and Kaplan-Meier survival analyzes was performed. Results: From a group of 83 patients, 12 were lost for follow-up. Of 71, 57 (80.3%) were men; age was 50 ± 12 years and they were followed by 73 ± 50 months. Fifteen (21,4%) patients showed right ventricular dysfunction, 13 (18,8%) had dilatation of the right ventricle and mean left ventricular ejection fraction was 27.1 ± 10.3%. Mitral regurgitation (moderate to severe) was present in 31 (34,3%) and 10 (14,5%) had AF. Fifteen (21.1%) patients died during follow-up and 11 (15.5%) were submitted to heart transplantation. Using Kaplan Meier analysis patients with right ventricular dysfunction showed a worse outcome, with difference in survival in both groups (p=0,016). Patients with right ventricular dysfunction had larger right ventricles (p= 0,000) and higher values of PASP (p=0,047), and also higher grades of mitral regurgitation (p= 0,001) and lower left ejection fraction (p=0,008). Even though the prevalence of AF was not higher in this patients (p=0,053), left atrial diameter was higher (p=0,00). Conclusions: In our group of patients, right ventricular dysfunction is a marker of worse prognosis as these patients show a lower survival throughout follow-up. Dilatation of right ventricle and PASP correlate with right ventricular dysfunction as well as higher grade mitral regurgitation and higher left atrial diameter.

Language: English

Type (Professor's evaluation): Scientific

Notes: Paiva M, Amorim S, Alves E, Campelo M, Moura B, Viana P, Silva Cardoso J, Maciel MJ. Right Ventricular Dysfunction in Dilated Cardiomyopathy – a Dim Outcome. Eur J Heart Fail Suppl 2012; 11(Suppl 1): P257. ISSN 1567-4215. Heart Failure Congress 2012, Belgrade, 2012