Abstract (EN):
Background: Stress cardiomyopathy (SC) is a rare acute cardiac syndrome characterized by acute transient left ventricular (LV) dysfunction of uncertain cause. Current data suggest an excellent outcome for patients with SC. We thought to evaluate the in-hospital and long-term outcome of patients (pts) diagnosed with SC in our tertiary referral center.
Methods: Retrospective analysis of all pts hospitalized between November 2006 and August 2011, fulfilling the Mayo Clinic criteria for the diagnosis of SC. Clinical features, complications, baseline and follow-up echocardiograms and cardiac magnetic resonance imaging were reviewed.
Results: We identified 37 consecutive pts, with a mean age of 63 ± 13 years. Women comprised 95% of all pts. A precipitating stressor event was found in 78% of pts, 57% being emotional triggers. Chest pain was the commonest symptom (89%). Three pts presented with dyspnoea (8%). ST segment elevation (32%) and global T wave inversion (41%) were the most frequent ECG changes. Troponin I was positive in all cases with a mean peak level of 2.6 ± 1.8 ng/ml. LV assessment demonstrated typical apical ballooning in 36 pts (inverted variant in one patient), with severe dysfunction in 43%. Late gadolinium enhancement was present only in one case. In -hospital complications occurred in 10 pts (30%) and included acute pulmonary oedema (n=2), cardiogenic shock (n=4); atrial fibrillation (n=1), left ventricular thrombus (n=2), third degree AV-block (n=1) and significant LV outflow gradient (n=2). There were no in-hospital deaths. Thirty five patients had follow-up, at mean time of 482 ± 512 days. We registered one death (hemorrhagic cerebrovascular event). No rehospitalizations or recurrences of SC were identified. Only 22 pts (62,8%) were asymptomatic (chest pain n=6; dyspnoea n=12).
Conclusions: In our population SC was associated with significant morbidity at short-term. At long-term recurrence of symptoms was common but the prognosis remained favourable with no recurrence of SC.
Language:
English
Type (Professor's evaluation):
Scientific
Notes:
Ribeiro V, Vasconcelos M, Ferreira E, Melão F, Malangatana G, Maciel MJ. Short and long-term outcome of Stress Cardiomyopathy: what can we expect? Eur J Heart Fail Suppl 2012; 11(Suppl 1): P263. ISSN 1567-4215 Heart Failure Congress 2012, Belgrade, 2012