DILTIAZEM EFFECTS ON LEFT-VENTRICULAR FUNCTION PRELIMINARY-RESULTS OF 12 PATIENTS EVALUATED BY CALIBRATED APEXCARDIOGRAM

• Type: Article in International Scientific Journal
• Date: 1995

Authors

CARDOSO, J (Author) FMUP; SILVA, JC (Author) Other; COUTINHO, J (Author) Other; CAMPELO, M (Author) FMUP; SIMOES, L (Author) Other; MACIEL, MJ (Author) FMUP; RAMALHAO, C (Author) Other

Journal

Title: Acta Cardiologica

Vol. 50 No. 1

Pages: 35-38

ISSN: 0001-5385

Publisher: Taylor & Francis

Indexing

ISI Web of Knowledge - 2 Citations

ISI Web of Science

Scopus - 2 Citations

Pubmed / Medline

Scientific classification

FOS: Medical and Health sciences > Clinical medicine

Other information

Authenticus ID: P-001-HE1

Abstract (EN): Diltiazem is a calcium channel blocker whose effects on left ventricular function (LVF) are controversial. We studied 12 patients with ischemic heart disease (IHD) before starting and 15 and 30 days after having initiated Diltiazem 60 mg t.i.d. LVF was accessed by means of she normalized indexes of the calibrated apexcardiogram: nS for systolic LVF evaluation and nA for diastolic LVF evaluation. Recent works have shown that these indexes have a good correlation with invasive parameters of LVF. We verified that nS did not change and nA decreased significantly (p<0.05) after Diltiazem. We preliminary concluded that Diltiazem has no deleterious effect on LV systolic function and improves LV diastolic function, by decreasing nA, a parameter which correlates well with LV end diastolic pressure.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4