Abstract (EN):
Introduction: Diabetes mellitus is one of the modifiable coronary risk factors of main focus in cardiac rehabilitation (CR) after an acute coronary syndrome (ACS).
Methods: Prospective study involving patients referred to a CR program after ACS, between September 2008 and November 2010. Baseline and after CR evaluations included functional capacity (FC), assessed through maximal metabolic equivalents (METS) achieved and total time (TTPE) to peak exercise at standard exercise testing. We used independent sample t-test and paired sample t test for between-group and intra-group differences. Survival analysis was done using cox-regression method.
Results: Two-hundred and forty-nine patients were evaluated, mean age was 54±10 years and 222 (89,2%) were men. Forty-nine (19,7%) were diabetic of which were 9 (18.4%) women. Diabetics were older, more frequently women, and showed worse cardiovascular risk profile with higher proportion of smokers, overweight patients and unfavorable body composition. Moreover, the diabetics had more extensive coronary heart disease and had higher proportions of CABG.
Only the non-diabetic patients showed significant improvement in FC (0,9±1,7 p=0,001 vs 0,3±1,2 p=0,15) and in TTPE (55±97p=0,001 vs 16±92 p=0,39).
These patients were followed for 11,4±8,6 months. Using cox-regression analysis Diabetes mellitus was associated with a higher probability of suffering and adverse cardiovascular outcome (16,7% vs 8%), although significance failed to be demonstrated possibly due to short follow-up duration.
Conclusions: Even though diabetics improve their FC and TTPE they do not show statistical significance improvement. Diabetics show a higher tendency for events throughout follow-up. This suggests that a longer follow-up might be needed to better assess these patients.
Language:
English
Type (Professor's evaluation):
Scientific
Notes:
Paiva M, Rocha A, Correia AS, Lebreiro A, Sousa A, Sousa C, Rangel I, Araújo V, Parada F, Maciel MJ. Diabetes mellitus in cardiac rehabilitation program – facing a challenge. Eur Heart J 2012; 33 (Abstract Suppl): 1058