Oral squamous cell carcinoma: Review of prognostic and predictive factors

• Type: Article in International Scientific Journal
• Date: 2006

Authors

João Massano (Author) Other; Regateiro, FS (Author) Other; Januario, G (Author) Other; Ferreira, A (Author) Other

Journal

Title: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics

Vol. 102

Pages: 67-76

ISSN: 1079-2104

Publisher: Mosby - Elsevier

Indexing

ISI Web of Knowledge - 420 Citations

Scopus - 451 Citations

Pubmed / Medline

Scientific classification

CORDIS: Health sciences > Medical sciences > Medicine > Oncology

Other information

Authenticus ID: P-004-K13

DOI: 10.1016/j.tripleo.2005.07.038

Abstract (EN): Oral squamous cell carcinoma has a remarkable incidence worldwide and a fairly onerous prognosis encouraging further research on factors that might modify disease Outcome. In this review article, the authors approach the factors that may exert influence on the prognosis and eventually guide the selection of patients for more aggressive therapies. Published scientific data was collected, selected, and grouped into 3 main clusters: patient-, tumor-, and treatment-related factors. Well established aspects are discussed, but also those less common or with only supposed usefulness. Disease staging extracapsular dissemination, resection margin free of disease, and tumor thickness are factors with high influence on the prognosis. There has been an increasing interest in the study Of tumor molecular factors, and some have been strongly correlated with the Outcome, showing promising pathways for the future development of more effective prognosis systems and anticancer therapies.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 10