Chitosan microparticles as injectable scaffolds for tissue engineering

• Type: Article in International Scientific Journal
• Date: 2008

Authors

Cruz, DMG (Author) Other; Ivirico, JLE (Author) Other; Gomes, MM (Author) Other; Ribelles, JLG (Author) Other; Sanchez, MS (Author) Other; Rui Reis (Author) Other; Mano, JF (Author) Other

Journal

Title: Journal of tissue engineering and regenerative medicine

Vol. 2

Pages: 378-380

ISSN: 1932-6254

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 58 Citations

Scopus - 60 Citations

Other information

Authenticus ID: P-003-XGB

DOI: 10.1002/term.106

Abstract (EN): The use of chitosan microparticles as injectable carriers for cell transplantation represents a promising alternative to avoid the drawbacks of the implantation of other forms of three-dimensional (3D) scaffolds seeded with cells. In this study, a 3D construct is obtained in vitro by combining chitosan microparticles crosslinked with genipin and goat bone marrow stromal cells (GBMCs). Cell viability and the morphology of GBMCs were evaluated after culture for 7 and 14 days. Our results show the feasibility of chitosan microparticles as potential injectable scaffolds for tissue engineering and regenerative medicine. Copyright (C) 2008 John Wiley & Sons, Ltd.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3