Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dog

• Type: Article in International Scientific Journal
• Date: 2011

Authors

Sousa, CP (Author) Other; Nery, F (Author) Other; Azevedo, JT (Author) Other; Viegas, CA (Author) Other; Gomes, ME (Author) Other; Dias, IR (Author) Other

Journal

Title: Arquivo Brasileiro de Medicina Veterinaria e Zootecnia

Vol. 63

Pages: 40-45

ISSN: 0102-0935

Publisher: Universidade Federal de Minas Gerais

Indexing

ISI Web of Knowledge - 5 Citations

Scopus - 7 Citations

Other information

Authenticus ID: P-002-VGN

DOI: 10.1590/s0102-09352011000100007

Abstract (EN): Values of serum tartrate-resistant acid phosphatase (TRAP) activity were obtained in adult dogs and its biological variability was assessed. Nine healthy skeletally mature Portuguese Podengo dogs were used for the determination of TRAP, total and bone alkaline phosphatase serum activities, and also to study their relationship with serum minerals, namely calcium (Ca), phosphorous (P), and magnesium (Mg). The serum TRAP activity was 2.19 +/- 0.56IU/mL, with intra-individual variation of 18.3% and inter-individual variation of 25.6%. Significant correlations were observed between serum TRAP activity and Ca (r=-0.3431; P<0.05), Ca and Mg (r=-0.787; P<0.01), and TRAP and Mg (r=0.397; P<0.05). The results indicate that serum TRAP activity in dog could be of great value in research and in clinical practice, providing complementary non-invasive information on bone metabolism.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6