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Merodrimanes and Other Constituents from Talaromyces thailandiasis

Title
Merodrimanes and Other Constituents from Talaromyces thailandiasis
Type
Article in International Scientific Journal
Year
2007
Authors
Tida Dethoup
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Leka Manoch
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Anake Kijjoa
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Madalena Pinto
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Luis Gales
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Ana Margarida Damas
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Artur M. S. Silva
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Graham Eaton
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Werner Herz
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Journal
Vol. 70 No. 7
Pages: 1200-1202
ISSN: 0163-3864
Indexing
Publicação em ISI Web of Science ISI Web of Science
Publicação em Scopus Scopus - 17 Citations
Scientific classification
FOS: Medical and Health sciences > Other medical sciences
CORDIS: Health sciences
Other information
Authenticus ID: P-004-952
Resumo (PT): Chemical study of a previously undescribed fungus, Talaromyces thailandiasis, furnished the two new merodrimanes thailandolides A (1) and B (2), an O-methylated derivative (3) of the aromatic fragment incorporated in thailandolide B, and three known closely related 1(3H)-isobenzofuran derivatives, penisimplicissin (4a), vermistatin (4b), and hydroxydihydrovermistatin (4c). Structures were established by spectroscopic measurements and confirmed by X-ray analyses of compounds 1 and 4b. The unusual peptide analogue N-benzoylphenylalanyl-N-benzoylphenyl alaninate (5) isolated earlier from a higher plant was also found. <br> <br> <a target="_blank" href="http://pubs.acs.org/doi/abs/10.1021/np0680578"> Texto integral</a> <br> <br>
Abstract (EN): Chemical study of a previously undescribed fungus, Talaromyces thailandiasis, furnished the two new merodrimanes thailandolides A (1) and B (2), an O-methylated derivative (3) of the aromatic fragment incorporated in thailandolide B, and three known closely related 1(3H)-isobenzofuran derivatives, penisimplicissin (4a), vermistatin (4b), and hydroxydihydrovermistatin (4c). Structures were established by spectroscopic measurements and confirmed by X-ray analyses of compounds 1 and 4b. The unusual peptide analogue N-benzoylphenylalanyl-N-benzoylphenyl alaninate (5) isolated earlier from a higher plant was also found. <br> <br> <a target="_blank" href="http://pubs.acs.org/doi/abs/10.1021/np0680578"> Full text </a> <br> <br>
Language: English
Type (Professor's evaluation): Scientific
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