Phenolics and antimicrobial activity of traditional stoned table olives ‘alcaparra’

• Type: Article in International Scientific Journal
• Date: 2006

Authors

Anabela Sousa (Author) Other; Isabel C.F.R. Ferreira (Author) Other; Ricardo Calhelha (Author) Other; Paula B. Andrade (Author) FFUP; Patrícia Valentão (Author) FFUP; Rosa Seabra (Author) FFUP; Letícia Estevinho (Author) Other; Albino Bento (Author) Other; José Alberto Pereira (Author) Other

Journal

Title: Bioorganic and Medicinal Chemistry

Vol. 14 No. 24

Pages: 8533-8538

ISSN: 0968-0896

Publisher: Elsevier

Indexing

ISI Web of Science

Scientific classification

FOS: Medical and Health sciences > Other medical sciences

CORDIS: Health sciences

Other information

Resumo (PT): In the present work, we report the determination of phenolic compounds in ‘alcaparra’ table olives by reversed-phase HPLC/DAD, and the evaluation of their extract in vitro activity against several microorganisms that may be causal agents of human intestinal and respiratory tract infections, namely Gram positive (Bacillus cereus, Bacillus subtilis, and Staphylococcus aureus), Gram negative bacteria (Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae) and fungi (Candida albicans and Cryptococcus neoformans). Three flavonoidic compounds were identified and quantified: luteolin 7-O-glucoside, apigenin 7-O-glucoside, and luteolin. At low concentrations (0.05 mg/mL) ‘alcaparra’ extract revealed significant inhibition of both Gram positive and Gram negative bacteria growth, with exception of P. aeruginosa. Nevertheless, no antifungal activity was observed at the tested concentrations. <br> <br> <a target="_blank" href="http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TF8-4KW5W94-3&_user=2460038&_coverDate=12%2F15%2F2006&_rdoc=39&_fmt=high&_orig=browse&_srch=doc-info(%23toc%235220%232006%23999859975%23636631%23FLA%23display%23Volume)&_cdi=5220&_sort=d&_docanchor=&_ct=61&_acct=C000057398&_version=1&_urlVersion=0&_userid=2460038&md5=02f2337f65a83f3efad714250fa9ebbb"> Texto integral </a> <br> <br>

Abstract (EN): In the present work, we report the determination of phenolic compounds in ‘alcaparra’ table olives by reversed-phase HPLC/DAD, and the evaluation of their extract in vitro activity against several microorganisms that may be causal agents of human intestinal and respiratory tract infections, namely Gram positive (Bacillus cereus, Bacillus subtilis, and Staphylococcus aureus), Gram negative bacteria (Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae) and fungi (Candida albicans and Cryptococcus neoformans). Three flavonoidic compounds were identified and quantified: luteolin 7-O-glucoside, apigenin 7-O-glucoside, and luteolin. At low concentrations (0.05 mg/mL) ‘alcaparra’ extract revealed significant inhibition of both Gram positive and Gram negative bacteria growth, with exception of P. aeruginosa. Nevertheless, no antifungal activity was observed at the tested concentrations. <br> <br> <a target="_blank" href="http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TF8-4KW5W94-3&_user=2460038&_coverDate=12%2F15%2F2006&_rdoc=39&_fmt=high&_orig=browse&_srch=doc-info(%23toc%235220%232006%23999859975%23636631%23FLA%23display%23Volume)&_cdi=5220&_sort=d&_docanchor=&_ct=61&_acct=C000057398&_version=1&_urlVersion=0&_userid=2460038&md5=02f2337f65a83f3efad714250fa9ebbb"> Full text </a> <br> <br>

Language: Portuguese

Type (Professor's evaluation): Scientific