Chemical Assessment and in Vitro Antioxidant Capacity of Ficus carica Latex

• Type: Article in International Scientific Journal
• Date: 2010

Authors

Andreia P Oliveira (Author) Other; Luis R Silva (Author) Other; Federico Ferreres (Author) Other; de Pinho, PG (Author) FFUP; Patricia Valentao (Author) FFUP; Branca M Silva (Author) Other; Jose A Pereira (Author) Other; Paula B Andrade (Author) FFUP

Journal

Title: Journal of Agricultural and Food Chemistry

Vol. 58

Pages: 3393-3398

ISSN: 0021-8561

Publisher: American Chemical Society

Indexing

ISI Web of Knowledge - 43 Citations

ISI Web of Science

Scopus - 52 Citations

Pubmed / Medline

Scientific classification

FOS: Agrarian Sciences > Other Agrarian Sciences

CORDIS: Health sciences > Pharmacological sciences > Pharmacognosy

Other information

Authenticus ID: P-003-87F

DOI: 10.1021/jf9039759

Resumo (PT): Ficus species possess latex-like material within their vasculatures, affording protection and self-healing from physical attacks. In this work, metabolite profiling was performed on Ficus carica latex. Volatiles profile was determined by HS-SPME/GC−IT-MS, with 34 compounds being identified, distributed by distinct chemical classes: 5 aldehydes, 7 alcohols, 1 ketone, 9 monoterpenes, 9 sesquiterpenes and 3 other compounds. Sesquiterpenes constituted the most abundant class in latex (ca. 91% of total identified compounds). Organic acids composition was also characterized, by HPLC−UV, and oxalic, citric, malic, quinic, shikimic and fumaric acids were determined. Malic and shikimic acids were present in higher amounts (ca. 26%, each). The antioxidant potential of this material was checked by distinct in vitro chemical assays. A concentration-dependent activity was noticed against DPPH, nitric oxide and superoxide radicals. Additionally, acetylcholinesterase inhibitory capacity was evaluated, but a weak effect was found. <br> <br> Keywords (keywords): Ficus carica latex; volatiles; organic acids; antioxidant potential; acetylcholinesterase inhibition <br> <a target="_blank" href="http://pubs.acs.org/doi/abs/10.1021/jf9039759 "> Texto integral </a> <br> <br>

Abstract (EN): Ficus species possess latex-like material within their vasculatures, affording protection and self-healing from physical attacks. In this work, metabolite profiling was performed on Ficus carica latex. Volatiles profile was determined by HS-SPME/GC-IT-MS, with 34 compounds being identified, distributed by distinct chemical classes: 5 aldehydes, 7 alcohols, 1 ketone, 9 monoterpenes, 9 sesquiterpenes and 3 other compounds. Sesquiterpenes constituted the most abundant class in latex (ca. 91% of total identified compounds). Organic acids composition was also characterized, by HPLC-UV, and oxalic, citric, malic, quinic, shikimic and fumaric acids were determined. Malic and shikimic acids were present in higher amounts (ca. 26%, each). The antioxidant potential of this material was checked by distinct in vitro chemical assays. A concentration-dependent activity was noticed against DPPH, nitric oxide and superoxide radicals. Additionally, acetylcholinesterase inhibitory capacity was evaluated, but a weak effect was found.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6