Kalanchosine Dimalate, an Anti-inflammatory Salt from Kalanchoe brasiliensis

• Type: Article in International Scientific Journal
• Date: 2006

Authors

Sônia Soares Costa (Author) Other; Maria de Lourdes Mendes de Souza (Author) Other; Tereza Ibrahim (Author) Other; Giany Oliveira de Melo (Author) Other; Ana Paula Almeida (Author) FFUP; Catherine Guette (Author) Other; Jean-Pierre Férézou (Author) Other; Vera Lucia G. Koatz (Author) Other

Journal

Title: Journal of Natural Products

Vol. 69 No. 5

Pages: 815-818

ISSN: 0163-3864

Publisher: American Chemical Society

Indexing

ISI Web of Science

Scientific classification

FOS: Medical and Health sciences > Other medical sciences

CORDIS: Health sciences

Other information

Resumo (PT): This report describes the isolation and characterization of kalanchosine dimalate (KMC), an anti-inflammatory salt from the fresh juice of the aerial parts of Kalanchoe brasiliensis. KMC comprises the new metabolite kalanchosine (1) and malic acid (2) in a 1:2 stoichiometric ratio. Kalanchosine (1), 3,6-diamino-4,5-dihydroxyoctanedioic acid, is the first naturally occurring dimeric bis(γ-hydroxy-β-amino acid) and is at least partially responsible for the anti-inflammatory properties of K. brasiliensis <br> <br> <a target="_blank" href="http://pubs.acs.org/doi/abs/10.1021/np050475%2B">Texto integral </a> <br> <br>

Abstract (EN): This report describes the isolation and characterization of kalanchosine dimalate (KMC), an anti-inflammatory salt from the fresh juice of the aerial parts of Kalanchoe brasiliensis. KMC comprises the new metabolite kalanchosine (1) and malic acid (2) in a 1:2 stoichiometric ratio. Kalanchosine (1), 3,6-diamino-4,5-dihydroxyoctanedioic acid, is the first naturally occurring dimeric bis(γ-hydroxy-β-amino acid) and is at least partially responsible for the anti-inflammatory properties of K. brasiliensis <br> <br> <a target="_blank" href="http://pubs.acs.org/doi/abs/10.1021/np050475%2B"> Full text</a> <br> <br>

Language: English

Type (Professor's evaluation): Scientific