Go to:
Logótipo
Comuta visibilidade da coluna esquerda
Você está em: Start > Publications > View > From waste to bioactive compounds: A response surface methodology approach to extract antioxidants from Pistacia vera shells for postprandial hyperglycaemia management
Publication

Publications

From waste to bioactive compounds: A response surface methodology approach to extract antioxidants from Pistacia vera shells for postprandial hyperglycaemia management

Title
From waste to bioactive compounds: A response surface methodology approach to extract antioxidants from Pistacia vera shells for postprandial hyperglycaemia management
Type
Article in International Scientific Journal
Year
2024
Authors
Maccarronello, AE
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Cardullo, N
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Silva, AM
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Di Francesco, A
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Paulo Costa
(Author)
FFUP
View Personal Page You do not have permissions to view the institutional email. Search for Participant Publications View Authenticus page View ORCID page
Rodrigues, F
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Muccilli, V
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Journal
Title: Food ChemistryImported from Authenticus Search for Journal Publications
Vol. 443
ISSN: 0308-8146
Publisher: Elsevier
Indexing
Publicação em ISI Web of Knowledge ISI Web of Knowledge - 0 Citations
Publicação em Scopus Scopus - 0 Citations
Other information
Authenticus ID: P-00Z-XD7
Abstract (EN): Pistacia vera shells, an abundant agricultural by-product, are a rich source of undiscovered bioactive compounds. This study employed a response surface methodology (RSM) approach to optimize the microwave-assisted extraction of antioxidants. The highest total phenolic content, and antioxidant activity were achieved under the optimized extraction conditions (20 % ethanol, 1000 W, 135 s, and solvent-to-solid ratio of 27 mL/g). The resulting extract (OPVS-E) included gallic acid derivatives, hydrolysable tannins, flavonoids, fatty acids, and anacardic acids. Remarkably, OPVS-E displayed potent inhibitory activity against alpha-amylase (IC50 = 2.05 mu g/mL) and alpha-glucosidase (IC50 = 41.07 mu g/mL), by far more powerful than the anti-diabetic drug acarbose, OPVS-E exhibited a strong antiradical capacity against reactive oxygen species (ROS) without causing toxicity in intestinal cells (HT29-MTX and Caco-2). These findings introduce OPVS-E as a potential novel dual-action nutraceutical ingredient, able to mitigate postprandial hyperglycemia and counteract the ROS overproduction occurring in type 2 diabetes mellitus.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 13
Documents
We could not find any documents associated to the publication.
Related Publications

Of the same authors

Unlocking the nutraceutical potential of Corylus avellana L. shells: microwave-assisted extraction of phytochemicals with antiradical and anti-diabetic properties (2024)
Article in International Scientific Journal
Maccarronello, AE; Cardullo, N; Silva, AM; Di Francesco, A; Paulo Costa; Rodrigues, F; Muccilli, V

Of the same journal

Vitamin D-fortified bread: Systematic review of fortification approaches and clinical studies (2022)
Another Publication in an International Scientific Journal
Souza, SVS; Borges, Nuno; Vieira, EF
Plant-derived and dietary phenolic cinnamic acid derivatives: Anti-inflammatory properties (2024)
Another Publication in an International Scientific Journal
Freitas, M; Ribeiro, D; Janela, JS; Varela, CL; Costa, SC; da Silva, ET; Eduarda Fernandes; Roleira, FMF
Plant derived and dietary phenolic antioxidants: Anticancer properties (2015)
Another Publication in an International Scientific Journal
Roleira, FMF; Tavares da Silva, EJ; Varela, CL; Costa, SC; Silva, T; Garrido, J; Fernanda Borges
Encapsulation in food industry with emerging electrohydrodynamic techniques: Electrospinning and electrospraying - A review (2021)
Another Publication in an International Scientific Journal
Sílvia Castro Coelho; Berta Nogueiro Estevinho; Fernando Rocha
Effects of pressure-based technologies on food lipids oxidation (2024)
Another Publication in an International Scientific Journal
Ganjeh, AM; Gomes, A; Barreira, MJ; Pinto, CA; Susana Casal; Saraiva, JA

See all (354)

Recommend this page Top
Copyright 1996-2025 © Faculdade de Direito da Universidade do Porto  I Terms and Conditions  I Acessibility  I Index A-Z
Page created on: 2025-07-14 at 18:35:23 | Privacy Policy | Personal Data Protection Policy | Whistleblowing