Laser surface modification of hydroxyapatite and glass-reinforced hydroxyapatite

• Type: Article in International Scientific Journal
• Date: 2004

Authors

Ana C. Queiroz (Author) Other; José D. Santos (Author) FEUP; Rui Vilar (Author) Other; Sónia Eugénio (Author) Other; Fernando J. Monteiro (Author) FEUP

Journal

Title: Biomaterials

Vol. 25 No. 13

Pages: 4607-4614

ISSN: 0142-9612

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 22 Citations

ISI Web of Science

Scopus - 26 Citations

COMPENDEX

Scientific classification

FOS: Engineering and technology > Environmental biotechnology

CORDIS: Technological sciences > Engineering > Biomaterial engineering ; Technological sciences > Engineering > Biomedical enginnering

Other information

Authenticus ID: P-000-92J

DOI: 10.1016/j.biomaterials.2003.11.054

Abstract (EN): Surface treatment of materials with excimer laser radiation often results in the formation of a rough columnar or cone-shaped surface topography, which leads to a considerable increase in the surface area. As a result, the search for a non-porous bioactive material with adequate mechanical properties and a high surface to volume ratio, similar to porous materials, which could be used for drug delivery in the treatment of periodontitis, justified assessing excimer laser surface treatment to promote controlled roughning of hydroxyapatite (HA) and glass-reinforced hydroxyapatite (GR-HA). A KrF excimer laser with 248nm radiation wavelength and 30 its pulse duration was used for surface modification. The laser treatment was carried out in air, using wide ranges of radiation fluence and number of laser pulses. In order to identify the physico-chemical changes induced by the laser treatment and the column formation mechanisms in these materials, the treated surfaces were characterised by laser profilometry, scanning electron microscopy (SEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and Fourier transform infra-red spectroscopy (FTIR). Laser processing induced the formation of a surface topography consisting of cone-shaped features. The constitution of the surface layer was also modified, as revealed by FTIR, XPS and XRD. This work has shown that laser surface modification increases the surface area of HA and GR-HA and is a promising technique to increase the reactivity and drug delivery capability of both materials.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8