Quality Control in Digital Pathology: Automatic Fragment Detection and Counting

• Type: Article in International Conference Proceedings Book
• Date: 2022

Authors

Albuquerque, T (Author) Other; Moreira, A (Author) Other; Barros, B (Author) Other; Montezuma, D (Author) Other; Oliveira, SP (Author) Other; Neto, PC (Author) Other; Monteiro, JC (Author) Other; Ribeiro, L (Author) Other; Gonçalves, S (Author) Other; Monteiro, A (Author) Other; Pinto, IM (Author) Other; Jaime S Cardoso (Author) FEUP

Conference proceedings International

Title: 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society, EMBC 2022, Glasgow, Scotland, United Kingdom, July 11-15, 2022

Pages: 588-593

Indexing

Scopus - 1 Citation

Other information

Authenticus ID: P-00X-6A4

DOI: 10.1109/embc48229.2022.9871208

Abstract (EN): Manual assessment of fragments during the pro-cessing of pathology specimens is critical to ensure that the material available for slide analysis matches that captured during grossing without losing valuable material during this process. However, this step is still performed manually, resulting in lost time and delays in making the complete case available for evaluation by the pathologist. To overcome this limitation, we developed an autonomous system that can detect and count the number of fragments contained on each slide. We applied and compared two different methods: conventional machine learning methods and deep convolutional network methods. For conventional machine learning methods, we tested a two-stage approach with a supervised classifier followed by unsupervised hierarchical clustering. In addition, Fast R-CNN and YOLOv5, two state-of-the-art deep learning models for detection, were used and compared. All experiments were performed on a dataset comprising 1276 images of colorec-tal biopsy and polypectomy specimens manually labeled for fragment/set detection. The best results were obtained with the YOLOv5 architecture with a map@0.5 of 0.977 for fragment/set detection.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5